Rhodium-Catalyzed Transannulation of 1,2,3-Thiazoles with Alkynes for the Direct Synthesis of Thiochromenones  

作　　者：Jun Pan Ziyao Zhang Lili Chen Ning Jiao 

机构地区：[1]State Key Laboratory of Natural and Biomimetic Drugs,Chemical Biology Center,Schoolof Pharmaceutical Sciences,Peking University XueYuanRd.38,Beijing 100191,China [2]Shanghai Key Laboratory of Green Chemistry and Chemical Processes,East China Normal University,Shanghai 200062,China

出　　处：《Chinese Journal of Chemistry》2023年第5期509-513,共5页中国化学（英文版）

基　　金：We acknowledge the National Key R&D Program of China(No.2021YFA1501700);the NSFC(Nos.22131002,22161142019,81821004);the Tencent Foundation for financial support.

摘　　要：A rhodium-catalyzed denitrogenative carbonylation of 1,2,3-thiadiazole with alkynes to construct(benzo)thiochromenones is developed.Both terminal and internal alkynes were compatible in this[3+2+1]cycloaddition,affording a broad range of poly-substituted thiochromenones.Unsymmetrical alkyne substrates exhibited good regioselectivity.

关 键 词：Rh-catalysis Transannulation THIADIAZOLES ALKYNES Thiochromenones 

分 类 号：O62[理学—有机化学]