基于CQ-11D、EQ-5D-3L和SF-6Dv1的中国一般人群健康相关生命质量测量结果的比较研究  

Study on Comparison of Health-related Quality of Life Measurements in General Populations in China Based on CQ-11D,EQ-5D-3L and SF-6Dv1

作　　者：周佳孟 朱文涛[1,2] 张梦培 谢诗桐 王葳 潘婕 吴晶[3] ZHOU Jiameng(School of management,Beijing University of Chinese Medicine,Beijing,100029,China)

机构地区：[1]北京中医药大学管理学院,北京100029 [2]北京中医药大学中药药物经济学评价研究所,北京100029 [3]天津大学药物科学与技术学院,天津300072 [4]加拿大麦克马斯特大学健康证据、方法与影响系,加拿大汉密尔顿,L8S4L8

出　　处：《医学与社会》2023年第5期116-121,共6页Medicine and Society

基　　金：国家自然科学基金资助项目,编号为71673197;中华中医药学会团体标准项目,编号为T/CACM1372-2021;中央高校基本科研业务专项,编号为2020-JYB-ZDGG-072。

摘　　要：目的:采用CQ-11D、EQ-5D-3L和SF-6Dv1共3种普适性健康效用量表,测量中国一般人群的健康相关生命质量并比较不同量表所得测量结果的差异,为中国人群健康相关生命质量研究提供参考。方法:依据中国一般人群分布区域、性别、年龄进行配额抽样,通过面对面调查收集受访者人口学特征信息,并依次收集CQ-11D、EQ-5D-3L和SF-6Dv1共3种量表的自报结果。选取其中未自报患慢性病的人群,描述其健康效用值情况,采用Tobit回归对健康效用值与主要人口学信息进行回归分析。结果:CQ-11D、EQ-5D-3L和SF-6Dv1量表的效用值均值分别为0.926、0.951及0.858。3种量表测量结果两两比较的一致性可信区间分别为(-0.1096,0.1593)、(-0.0827,0.1523)及(-0.0691,0.1626),组内相关系数分别为0.503、0.329和0.275。Tobit回归表明,性别与体育锻炼或健身活动均为3种量表的显著影响因素,但目前家庭与婚姻状况、吸烟等特征对3种量表的影响均有区别。结论:CQ-11D量表测量值总体低于EQ-5D-3L量表,但高于SF-6D v1量表。3种量表测量所得一般人群健康效用值间的一致性较好,但相关性较低,不同量表间影响因素存在一定差异。Objective:Three universal health utility scales,CQ-11D,EQ-5D-3L and SF-6Dv1,were used to measure the health-related quality of life of the Chinese general population,comparing the differences in the results obtained by different scales,so as to provide references for Chinese health-related quality of life study.Methods:Quota sampling was carried out according to the area,gender and age of the general population in China,and the socio-demographic characteristics of the respondents were collected through face-to-face surveys.This study selected people who did not self-report chronic diseases to describe the stratification and distribution of health utility values and Bland-Altman.Tobit regression was used to analyze the relationship between health utility value and main sociodemographic information.Results:The mean utility values of the CQ-11D,EQ-5D-3L and SF-6Dv1 scales were 0.926,0.951 and 0.858 respectively.The results of the consistency and correlation showed that the consistency credible intervals for the pairwise comparison of the three scales were(-0.1096,0.1593),(-0.0827,0.1523)and(-0.0691,0.1626),and the ICC results were 0.503,0.329 and 0.275.Tobit regression results showed that gender and physical activity or fitness activity were significant in all three scales,the effects of current marital status and smoke on the three scales were different.Conclusions:The CQ-11D scale measures were generally lower than the EQ-5D-3L scale,but higher than the SF-6D v1 scale.The general population health utility values of the three scales were consistent,but the correlations were low.There were some differences in influencing factors among different scales.

关 键 词：健康相关生命质量 健康效用 中医生命质量评价量表 中国一般人群 

分 类 号：R195.4[医药卫生—卫生统计学]