细菌环二鸟苷酸介导的信号转导途径研究进展  

The Advance in Signaling Pathway Mediated by Cyclic Diguanosine Monophosphate in Bacteria

作　　者：黄玉珠 彭仁[1] HUANG Yuzhu;PENG Ren(College of Life Science,Jiangxi Normal University,Nanchang Jiangxi 330022,China)

机构地区：[1]江西师范大学生命科学学院,江西南昌330022

出　　处：《江西师范大学学报（自然科学版）》2023年第2期176-182,共7页Journal of Jiangxi Normal University(Natural Science Edition)

基　　金：国家自然科学基金(31960011,31560018)资助项目。

摘　　要：环二鸟苷酸(c-di-GMP)是在细菌中广泛存在的第二信使分子,它介导的信号转导途径涉及调控细菌的运动、致病性、生物膜形成、细胞周期进程和有机溶剂耐受性等多种重要功能.该文主要从c-di-GMP的合成与降解、c-di-GMP的效应子及c-di-GMP的生理作用3方面对c-di-GMP介导的信号转导途径进行总结,并对该信号转导途径的研究前景进行了展望.Cyclic diguanosine monophosphate(c-di-GMP)is one of second messengers,which is widely existed in bacteria.The signaling pathway mediated by c-di-GMP is involved in the regulation of various important functions in bacteria including motility,virulence,biofilm formation,cell cycle and organic solvents tolerance.In the present paper,the synthesis and degradation of c-di-GMP,the effectors of c-di-GMP and the physiological roles of c-di-GMP are summarized and the outlook in the signaling pathway research is presented.

关 键 词：环二鸟苷酸 效应子 信号转导途径 

分 类 号：Q935[生物学—微生物学] Q936