持续光照和熬夜对雌性生殖功能的影响  

Effects of Continuous Light and Staying Up Late on Female Reproductive Function

作　　者：杜文豪 高富敏 李小龙 欧湘红(审校) DU Wen-hao;GAO Fu-min;LI Xiao-long;OU Xiang-hong(Department of Obstetrics and Gynecology,Guangdong Second Provincial General Hospital,School of Medicine,Jinan University,Guangzhou 510317,China;Center of Reproductive Medicine,Guangdong Second Provincial General Hospital,School of Medicine,Jinan University,Guangzhou 510317,China;Hengyang Medical School,University of South China,Hengyang 421001,Hunan Province,China)

机构地区：[1]暨南大学医学部广东省第二人民医院妇产科,广州510317 [2]暨南大学医学部广东省第二人民医院生殖医学中心,广州510317 [3]南华大学衡阳医学院

出　　处：《国际生殖健康／计划生育杂志》2023年第3期245-249,共5页Journal of International Reproductive Health/Family Planning

基　　金：国家自然科学基金(81971357)。

摘　　要：近年来,轮班制度、加班、熬夜逐渐成为生活常态,越来越多的人长时间暴露在人造光源下,使光污染成为威胁人类尤其是城市人口健康的严峻问题之一。研究发现,持续光照和熬夜可能与女性月经紊乱、不孕、复发性流产等息息相关,其相关机制尚不清楚,可能通过抑制下丘脑-垂体-性腺轴,导致内分泌紊乱,卵泡发育异常,黄体功能不全以及机体的代谢紊乱。综述持续光照对女性生殖功能的影响、持续光照与不孕、复发性流产等之间的关系和可能的作用机制。In recent years,the shift system,overtime and staying up late have gradually become the life norm.More and more people have been exposed to artificial light sources for a long time,and light pollution has been identified as one of the major threats to human health,particularly among the urban population.Continuous lighting and staying up late have been linked to female menstrual disorders,infertility,recurrent spontaneous abortion,and other issues.The relevant mechanisms may include the endocrine disorder,abnormal follicular development,luteal dysfunction and metabolic disorders by inhibiting the hypothalamus-pituitary-gonad axis.However,the exact mechanisms are still unknown.We review the impact of continuous light on female reproductive function and the relationship between continuous light and infertility and recurrent spontaneous abortion,and possible mechanisms of action in this paper.

关 键 词：内分泌系统 昼夜节律 不育 女(雌)性 流产 习惯性 持续光照 

分 类 号：R339.22[医药卫生—人体生理学]