H_(2)O_(2)增敏羧甲基取代benzo[3]uril电化学发光识别琥珀酰胆碱  

Recognition Towards Succinylcholine by H_(2)O_(2)-Sensitized Electrochemiluminescence of Carboxymethyl-substituted Benzo[3]uril

作　　者：高瑞晗 邱菲 丛航[1] GAO Ruihan;QIU Fei;CONG Hang(Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province,Guizhou University,Guiyang 550025,China)

机构地区：[1]贵州省大环化学及超分子化学重点实验室,贵州贵阳550025

出　　处：《贵州大学学报（自然科学版）》2023年第3期25-29,共5页Journal of Guizhou University:Natural Sciences

基　　金：贵州省省级科技计划项目资助(黔科合基础-ZK[2022]一般049)。

摘　　要：电化学发光技术是一种高灵敏、快响应的化学分析手段。通过考察羧甲基取代benzo[3]uril的电化学发光机理,发现超氧自由基有助其电化学发光。因此,引入共反应试剂H_(2)O_(2)以达到增强羧甲基取代benzo[3]uril时所产生的电化学发光信号的目的,成功构建H_(2)O_(2)增敏羧甲基取代benzo[3]uril的电化学发光传感器用于对琥珀酰胆碱的高灵敏性进行检测,检出限低至1.0×10^(-15)mol/L。Electrochemiluminescence is a highly sensitive and fast-response chemical analysis method.By investigating the electrochemiluminescence mechanism of carboxymethyl-substituted benzo[3]uril,it was found that superoxide radicals contribute to its electrochemiluminescence.In this paper,the introduction of co-reactive reagent H_(2)O_(2)achieves the purpose of enhancing the electrochemiluminescence signal of carboxymethyl-substituted benzo[3]uril,and the H_(2)O_(2)sensitized carboxymethyl-substituted benzo[3]uril electrochemiluminescence sensor is successfully constructed for the detection of the high sensitivity of succinylcholine,with a detection limit as low as 1.0×10^(-15)mol/L.

关 键 词：电化学发光 uril 过氧化氢 琥珀酰胆碱 

分 类 号：O657.1[理学—分析化学]