2型糖尿病合并高血压患者颈动脉粥样硬化斑块形成的危险因素Logistic回归分析  

Logistic Regression Analysis of Risk Factors for Carotid Atherosclerotic Plaque Formation in Patients with Type 2 Diabetes Mellitus and Hypertension

作　　者：王琳[1] 马锦花 陈慧娟 李睿 鲍强 WANG Lin;MA Jin-hua;CHEN Hui-juan;LI Rui;BAO Qiang(Suining County People's Hospital,Xuzhou 221200,Jiangsu Province,China)

机构地区：[1]睢宁县人民医院,江苏徐州221200

出　　处：《罕少疾病杂志》2023年第5期22-24,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨分析2型糖尿病(T2DM)合并高血压(HBp)患者颈动脉粥样硬化斑块形成的危险因素。方法回顾187例T2DM合并HBp患者的临床资料,统计颈动脉粥样硬化斑块形成率,总结可能导致T2DM合并HBp患者形成颈动脉粥样硬化斑块的危险因素,给予描述性检验和Logistic回归分析。结果本组病例中共有82例形成颈动脉粥样硬化斑块,发生率为43.85%;形成组和未形成组在性别、BMI的构成比差异无统计学意义(P>0.05),形成组年龄>60岁、T2DM病程>10年、HBp病程>10年、HBp3级、HbAlc>7.1%、合并高脂血症、合并高血同型半胱氨酸症、吸烟指数>400支年/天的构成比均明显高于未形成组(P<0.05);经Logistic回归分析可知,年龄>60岁、T2DM病程>10年、HBp病程>10年、HBp 3级、HbAlc>7.1%、合并高脂血症、合并高同型半胱氨酸血症、吸烟指数>400支年/天均是T2DM合并HBp患者颈动脉粥样硬化斑块形成的独立危险因素(OR=3.651、3.074、3.123、5.244、6.190、3.999、7.185、3.070)。结论T2DM合并HBp患者颈动脉粥样硬化斑块形成率高,年龄>60岁、T2DM病程>10年、HBp病程>10年、HBp 3级、HbAlc>7.1%、合并高脂血症、合并高血同型半胱氨酸症及吸烟指数>400支年/天等均是其独立危险因素,需加强防控。Objective To explore the risk factors of carotid atherosclerotic plaque formation in patients with type 2 diabetes mellitus(T2DM)and high blood pressure(HBp).Methods The clinical data of 187 patients with T2DM and HBP were reviewed.The plaque formation rate of carotid atherosclerosis was calculated.To summarize the risk factors of carotid atherosclerotic plaque in T2DM patients with HBP,and to give descriptive test and logistic regression analysis.Results There were 82 cases of carotid atherosclerotic plaques in this group,the incidence was 43.85%.There were no significant difference between the two groups(P>0.05).The age>60 years old,the course of T2DM>10 years,the course of HBp>10 years,the level of HBp 3,HbAlc>7.1%,hyperlipidemia,hyperhomocysteinemia,smoking index>400 cigarette year/day of formation group were significantly higher than that of non-formation group(PP<0.05).According to logistic regression analysis,age>60 years old,T2DM course>10 years,HBp course>10 years,HBp Level 3,HbAlc>7.1%,hyperlipidemia,hyperhomocysteinemia,smoking index>400 cigarette year/day were independent risk factors for carotid atherosclerotic plaque formation in patients of T2DM with HBP(OR=3.651,3.074,3.123,5.244,6.190,3.999,7.185,3.070).Conclusion The rate of carotid atherosclerotic plaque formation was high in T2DM patients with HBp.Age>60 years old,course of T2DM>10 years,course of HBp>10 years,grade 3 of HBp,HbAlc>7.1%,hyperlipidemia,Hyperhomocysteine and smoking index>400 cigarette year/day were all independent risk factors,and prevention and control should be strengthened.

关 键 词：2型糖尿病 高血压 颈动脉粥样硬化 斑块 危险因素 LOGISTIC回归分析 

分 类 号：R714.2[医药卫生—妇产科学]