比较新型硅橡胶负压冲洗引流系统与聚氨酯负压引流系统体外防堵塞性能的观察  

Comparison of the anti-blocking performance between the new silicone rubber negative pressure drainage instillation system and the polyurethane negative pressure drainage system in vitro

作　　者：翟延荣[1] 朱亚萍[1] 张秀珍[1] 钟晓娟 鲁香月 张雨凡 陆树良[2] Zhai Yanrong;Zhu Yaping;Zhang Xiuzhen;Zhong Xiaojuan;Lu Xiangyue;Zhang Yufan;Lu Shuliang(Department of Wound Repair,People′s Hospital of Wuzhong,Suzhou 215128,China;Wound Repair Center,Ruijin Hospital,Shanghai Jiao Tong School of Medicine,Shanghai 200025,China)

机构地区：[1]苏州市吴中人民医院创面修复科,215128 [2]上海交通大学医学院附属瑞金医院创面修复中心,200025

出　　处：《中华损伤与修复杂志（电子版）》2023年第2期116-122,共7页Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)

基　　金：江苏省苏州市科技计划项目(SKY2022033)。

摘　　要：目的体外比较新型硅橡胶防堵负压冲洗引流系统与传统聚氨酯负压引流系统的防堵塞性能。方法设计一种体外防堵实验,以PVC板模拟伤口表面,建立体外创面负压封闭引流模型,并制作了4种不同粘度的液体模拟不同创面的渗液及坏死组织,4种液体分别为:1号液体(0.9%生理盐水)、2号液体(混合均匀的生鸡蛋清)、3号液体(20 g蛋清加入200 ml 100℃的水中混匀)、4号液体(2号液体与3号液体1∶1混匀),检测新型硅橡胶防堵负压冲洗引流管与传统聚氨酯负压材料在-50 mmHg至-300 mmHg负压条件下被4种液体体外灌洗后的堵塞情况。结果1~4号液体粘度分别为(1.16±0.01)mPa.S、(4.27±0.01)mPa.S、(1.26±0.02)mPa.S、(3.26±0.01)mPa.S;两种负压材料被4种液体灌洗后均出现不同程度的堵塞,负压明显减小(P<0.05),其中1号液体组,在-50 mmHg至-175 mmHg条件下,两组负压材料堵塞程度差异无统计学意义(P>0.05),但在-200 mmHg至-300 mmHg条件下聚氨酯负压材料组堵塞程度较防堵负压冲洗引流管组严重(P<0.05);在2~4号液体组,防堵负压冲洗引流管组堵塞程度均较传统聚氨酯负压材料组明显减轻(P<0.05)。结论本课题组发明设计的新型硅橡胶防堵负压冲洗引流系统防堵效果佳,可应用于渗液粘稠、坏死组织较多的创面。Objective To compare the anti-blocking performance between the new silicone rubber negative pressure drainage instillation system and traditional polyurethane negative pressure drainage system in vitro.Methods An in vitro anti-blocking experiment was designed.Established an wound vacuum sealing drainage model in vitro and simulated the wound surface with PVC plates.Liquid 1(0.9%saline),liquid 2(raw egg white mixed evenly),liquid 3(20 g egg white mixed in 200 ml of 100℃water)and liquid 4(liquid 2 and liquid 3 mixed in 1∶1)were used to simulate different exudates and necrotic tissues of the wound,and the blockage of the two groups of negative pressure materials after being irrigated by four kinds of liquids under negative pressure of-50 mmHg to-300 mmHg was detected.Results The viscosities of liquid 1 to liquid 4 were(1.16±0.01)mPa.S,(4.27±0.01)mPa.S,(1.26±0.02)mPa.S,(3.26±0.01)mPa.S.After the two negative pressure materials were irrigated with four kinds of liquids,they were both blocked,and the negative pressure was significantly reduced(P<0.05).In the liquid 1 group,under the conditions of-50 mmHg to-175 mmHg,there was no statistically significant difference in the blocking degree of the two kinds of negative pressure materials(P>0.05),but under the conditions of-200 mmHg to-300 mmHg,the blocking degree of the polyurethane negative pressure material was more serious than that of the anti-blocking negative pressure drainage tube with instillation(P<0.05).In the liquid 2-4 groups,the traditional polyurethane negative pressure material was significantly higher than the anti-blocking negative pressure drainage tube with instillation(P<0.05).Conluusion The new silicone rubber negative pressure drainage instillation system invented and designed by our group has good anti-blocking effect and can be applied to wounds with thick exudate and nonviable tissue.

关 键 词：负压伤口疗法 聚氨酯 管道堵塞 防堵负压冲洗引流管 

分 类 号：R641[医药卫生—外科学]