夹闭尿管与自然引流对留置导尿神经源性膀胱患者影响的Meta分析  

Effect of clamping catheter and free drainage for patients with neurogenic bladder with indwelling catheter:a meta-analysis

作　　者：朱亮 潘红霞 张建梅 胡静温 杜春萍 魏全 ZHU Liang;PAN Hongxia;ZHANG Jianmei;HU Jingwen;DU Chunping;WEI Quan(Department of Rehabilitation Medicine Center,West China Hospital/West China School of Nursing,Sichuan University,Chengdu 610041,P.R.China;Key Laboratory of Rehabilitation Medicine in Sichuan Province,Chengdu 61004l,P.R.China)

机构地区：[1]四川大学华西医院康复医学科/四川大学华西护理学院,成都610041 [2]康复医学四川省重点实验室,成都610041

出　　处：《中国循证医学杂志》2023年第4期422-425,共4页Chinese Journal of Evidence-based Medicine

摘　　要：目的系统评价夹闭尿管与自然引流对留置导尿神经源性膀胱患者的影响。方法计算机检索Pub Med、EMbase、CINAHL、EBSCO、Cochrane Library、CBM、CNKI、VIP和Wan Fang Data数据库,搜集与研究目的相关的随机对照试验(RCT),检索时限均为建库至2022年1月8日。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Rev Man 5.3软件进行Meta分析。结果共纳入7个RCT,包括586名患者。Meta分析结果显示,夹闭尿管组在首次排尿时间[SMD=-1.03,95%CI(-1.71,-0.36),P=0.03]和首次排尿量[MD=52.72,95%CI(28.84,76.59),P<0.01]方面优于自然引流组。但两组残余尿量、尿潴留和尿路感染发生率的差异无统计学意义。结论当前证据显示,夹闭尿管对留置尿管神经源性膀胱患者的优势并不明显。受纳入研究数量和质量的限制,上述结论尚待更多高质量研究予以验证。Objective To systematically review the effect of clamping catheter and free drainage for patients with neurogenic bladder with indwelling catheter.Methods The PubMed,EMbase,CINAHL,EBSCO,Cochrane Library,CBM,CNKI,VIP and WanFang Data databases were electronically searched to collect randomized controlled trials(RCTs)related to the objects from inception to January 8,2022.Two reviewers independently screened literature,extracted data and assessed the risk of bias of the included studies.Meta-analysis was then performed by using RevMan 5.3 software.Results A total of 7 RCTs involving 586 patients were included.Meta-analysis showed that clamping catheter significantly reduced time of first void(SMD=-1.03,95%CI-1.71 to-0.36,P-0.03)and increased volume of first void(MD=52.72,95%CI 28.84 to 76.59,P<0.01).However,there was no significant difference in residual urine volume,incidence of urinary retention or urinary tract infection between the two groups.Conclusion Current evidence shows that the advantage of clamping catheter for patients with neurogenic bladder with indwelling catheter is not obvious.Due to the limited quality and quantity of the included studies,more high quality studies are needed to verify the above conclusion.

关 键 词：神经源性膀胱 留置尿管 夹闭尿管 自然引流 系统评价 META分析 

分 类 号：R694[医药卫生—泌尿科学]