甘草浸膏超声辅助真空干燥传热传质模拟与试验  

Simulation and experiment of heat and mass transfer in ultrasound-assisted vacuum drying of licorice extract

作　　者：王学成 王晓辉 伍志成 张浩铭 王雅琪 李远辉 郑琴 易兵 刘振峰 伍振峰 杨明 WANG Xue-cheng;WANG Xiao-hui;WU Zhi-cheng;ZHANG Hao-ming;WANG Ya-qi;LI Yuan-hui;ZHENG Qin;YI Bing;LIU Zhen-feng;WU Zhen-feng;YANG Ming(Key Laboratory of Modern Preparation of Traditional Chinese Medicine,Ministry of Education,Jiangxi University of Chinese Medicine,Nanchang 330004,China;Jiangxi Hebai Kanghua Pharmaceutical Equipment Co.,Ltd.,Nanchang 330096,China;Yichun Wanshen Pharmaceutical Machinery Co.,Ltd.,Yichun 336000,China)

机构地区：[1]江西中医药大学现代中药制剂教育部重点实验室,江西南昌330004 [2]江西赫柏康华制药设备有限公司,江西南昌330096 [3]宜春万申制药机械有限公司,江西宜春336000

出　　处：《中草药》2023年第7期2056-2065,共10页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(82003952);国家自然科学基金资助项目(81960718);江西中医药大学中药制剂技术与制药装备创新团队(CXTD22006);中央引导地方科技发展资金项目(2022ZDD03085)。

摘　　要：目的以甘草浸膏为研究对象,探索浸膏超声辅助真空干燥强化传热传质机制,为新技术在中药浸膏干燥中的应用提供理论依据。方法基于过程模拟软件建立“超声场-温度场-压力场”多场耦合的甘草浸膏超声辅助真空干燥传热传质模型并求解;进行了干燥温度70、80、90℃,超声功率40、80、120、160、200 W的干燥试验,以特征点温度及干燥水分试验结果与模型计算理论值进行比较。结果甘草浸膏干燥过程水分有效扩散系数(Deff)和传质系数(kc)随温度和超声功率的升高而增大,超声功率由40 W提高至200 W,Deff及kc分别提高200.65%、154.46%;结果验证了建立的浸膏超声辅助真空干燥模型精度良好,在一定条件下能反映真实干燥过程。结论通过建立精度良好的甘草浸膏超声辅助真空干燥过程仿真模型,直观得到了浸膏内部超声场强分布及热质传递规律,为该技术用于中药浸膏高效干燥工艺开发和装备设计提供参考。Objective To explorethe mechanism of heat and mass transfer enhanced by ultrasound-assisted vacuum drying of licorice extract,so as toprovide a theoretical basis for the application of new technology in the drying of Chinese herbal extract.Methods A multi-field coupled“ultrasonic field-temperature field-pressure field”heat and mass transfer model of licorice ultrasound-assisted vacuum drying was established and solved.The drying temperature of 70,80,90℃,ultrasonic power of 40,80,120,160,200 W drying test of licorice extract was studied.The experimental results of characteristic point temperature anddry moisture were compared with the theoretical values calculated by the model.ResultsThe effective diffusivity of water(Deff)and mass transfer coefficient(kc)increased with the increase of temperature and ultrasonic power.When the ultrasonic power increased from 40 W to 200 W,Deffand kcincreased by 200.65%and 154.46%,respectively.The experimental results verifiedthat the established model of ultrasound-assisted vacuum drying of licorice extract hadgood accuracy and reflectedthe real drying process under certain conditions.ConclusionThe ultrasonic field intensity and heat and mass transfer law in the extract were obtained intuitively by establishing the simulation model of ultrasound-assisted vacuum drying process of licorice extract with good accuracy.The results provide reference for the application of this technology in the development of efficient drying process and equipment design of traditional Chinese herbal extract.

关 键 词：甘草浸膏 超声辅助真空干燥 过程模拟 传热传质 干燥效率 COMSOL Multiphysics 

分 类 号：R283.6[医药卫生—中药学]