党参治疗胃溃疡的作用机制研究进展  

Research progress on mechanism of action of Codonopsis Radix in treatment of gastric ulcer

作　　者：史奇 陈正君[1] 刘雪枫[1] 黄钰芳[1] 赵鲲鹏[1] 杨扶德[1] SHI Qi;CHEN Zheng-jun;LIU Xue-feng;HUANG Yu-fang;ZHAO Kun-peng;YANG Fu-de(Gansu University of Chinese Medicine,Lanzhou 730000,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000

出　　处：《中草药》2023年第7期2338-2348,共11页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(82160714);甘肃省科技计划项目(21JR1RA271);2021年度甘肃高等学校产业支撑计划项目(2021CYZC-40);国家科技部重点研发计划项目(2018YFC1706305)。

摘　　要：胃溃疡是一类患病率高的脾胃病,具有多发、易患、反复、难愈等特点。目前临床上已有众多相关治疗药物,然多数仅有助于缓解症状,难以根本治愈。党参具有健脾益肺、生津养血的功效,药效偏缓且滋益,在治疗胃溃疡方面具有突出疗效,能够有效降低溃疡指数、调节胃肠动力、加速溃疡愈合。通过检索查阅CNKI、万方、Pubmed等数据库文献,综合论述党参药材、党参提取物及其药效成分治愈胃溃疡的作用机制,以期为进一步深入挖掘党参在脾胃方面的应用价值提供科学依据和科研思路。Gastric ulcer is a type of spleen and stomach disease with a high prevalence rate,which has the characteristics of multiple,easy to suffer,repeated and difficult to heal.At present,there are many related therapeutic drugs in clinical practice,but most of them are only effective in relieving symptoms and cannot be cured fundamentally.Codonopsis Radix has the effect of invigorating spleen and lung,nourishing body fluid and blood,the effect is slow and nourishing,it has outstanding curative effect in the treatment of gastric ulcer,which can effectively reduce the ulcer index,regulate gastrointestinal motility,and accelerate ulcer healing.In this paper,by searching and consulting databases such as CNKI,Wanfang Database,Pubmed,etc,this paper comprehensively discusses the mechanism of action of Codonopsis Radix,Codonopsis Radix extracts and its medicinal components in the research on curing gastric ulcer,in order to provide certain scientific basis and scientific research ideas for further explore the application value of Codonopsis Radix in the spleen and stomach.

关 键 词：党参 胃溃疡 健脾调胃 作用机制 抗溃疡中药 

分 类 号：R286[医药卫生—中药学]