定向透药疗法联合塞来昔布治疗对老年股骨颈骨折髋关节置换术后患者疼痛、髋关节功能的影响  

Effect of Targeted Transdermal Drugs Combined with Celecoxib for Pain and Hip Joint Function in Senile Patients with Femoral Neck Fracture After Hip Replacement

作　　者：路绪超 张卫帅 刘江涛 朱贤友 LU Xuchao;ZHANG Weishuai;LIU Jiangtao;ZHU Xianyou

机构地区：[1]开封市人民医院骨科,河南开封475000

出　　处：《新中医》2023年第8期111-115,共5页New Chinese Medicine

基　　金：开封市骨科微创治疗重点实验室(汴科文[2020]67号)。

摘　　要：目的:观察定向透药疗法联合塞来昔布治疗对老年股骨颈骨折髋关节置换术后患者疼痛、髋关节功能的影响。方法:选取150例行髋关节置换术治疗的老年股骨颈骨折患者,以随机数字表法分为对照组和治疗组各75例。2组术后均给予抗感染、预防血栓等治疗,对照组在此基础上加用塞来昔布治疗,治疗组在对照组基础上给予定向透药疗法治疗,2组均治疗14 d,随访3个月。比较2组临床疗效、视觉模拟评分法(VAS)评分、Harris评分、并发症发生率、首次下床活动时间及住院时间。结果:术后第14天,2组VAS评分均较术后第1天降低(P<0.05),治疗组VAS评分低于对照组(P<0.05)。术后第14天、随访3个月,2组Harris评分均较术后第1天升高(P<0.05),治疗组Harris评分高于同期对照组(P<0.05)。术后14 d,治疗组并发症总发生率4.00%,低于对照组13.33%(P<0.05)。治疗组术后首次下床活动时间、住院时间均短于对照组(P<0.05)。结论:定向透药疗法联合塞来昔布治疗对老年股骨颈骨折髋关节置换术后患者具有较好的效果,可减轻疼痛、改善髋关节功能、减少并发症,促进患者术后尽早下床活动,缩短住院时间。Objective:To observe the effect of targeted transdermal drugs combined with Celecoxib on pain and hip joint function in senile patients with femoral neck fracture after hip replacement.Methods:A total of 150 cases of senile patients with femoral neck fracture after hip replacement were selected and divided into the control group and the treatment group according to the random number table method,with 75 cases in each group.Both groups were given treatments including anti-infection and prevention of thrombosis after surgery;the control group was additionally treated with Celecoxib,and the treatment group was additionally treated with targeted transdermal drugs based on the treatment of the control group.Both groups were treated for 14 days and followed up for 3 months.The clinical effects,Visual Analogue Scale(VAS)scores,Harris scores,the incidence of complications,the time of the first out-of-bed activity,and the hospitalization time were compared between the two groups.Results:On the fourteenth day after surgery,the VAS scores in the two groups were decreased when compared with those on the first day after surgery(P<0.05),and the VAS score in the treatment group was lower than that in the control group(P<0.05).On the fourteenth day after surgery and after a 3-month follow-up,the Harris scores in the two groups were increased when compared with those on the first day after surgery (P<0.05),and the Harris scores in the treatment group were higher than those in the control group at thesame time (P<0.05). fourteen days after surgery,the total incidence of complications was 4.00% in thetreatment group,lower than that of 13.33% in the control group (P<0.05). The time of the first out-of-bedactivity and the hospitalization time in the treatment group were shorter than those in the control group (P<0.05). Conclusion: Targeted transdermal drugs combined with Celecoxib has a good effect on senilepatients with femoral neck fracture after hip replacement, which can reduce pain, improve hip jointfunction,reduce complications

关 键 词：股骨颈骨折 老年人 髋关节置换术 定向透药疗法 塞来昔布 疼痛 髋关节功能 并发症 

分 类 号：R683.42[医药卫生—骨科学]