心功能不全气虚血瘀证患者血粘度变化研究  

Changes of blood viscosity in patients with Qi deficiency and blood stasis syndrome of cardiac insufficiency

作　　者：牛耀杰 赫俊芬 贾晓旭 NIU Yao-jie;HE Jun-fen;JIA Xiao-xu(Department of Rheumatology,Erdos Hospital of Traditional Chinese Medicine,Ordos 017010,China)

机构地区：[1]鄂尔多斯市中医医院风湿病科,017010 [2]鄂尔多斯市中医医院药剂科,017010 [3]达拉特旗中蒙医医院风湿病科,014300

出　　处：《中国实用医药》2023年第9期133-136,共4页China Practical Medicine

基　　金：2017年度自治区卫生计生科研计划项目(项目编号:201703246)。

摘　　要：目的探讨心功能不全气虚血瘀证患者血粘度变化情况。方法选取51例心功能不全气虚血瘀证患者作为病例组,另选取23例健康体检者作为健康对照组。两组均进行全血粘度及血浆粘度检测。分析不同年龄段心功能不全气虚血瘀证患者全血粘度、血浆粘度情况,对比两组全血粘度(全血粘度低切、全血粘度中切、全血粘度高切)及血浆粘度检测结果。结果50~69岁患者全血粘度增高13例(72.2%),正常5例(27.8%);70~79岁患者全血粘度增高14例(77.8%),正常4例(22.2%);80~89岁患者全血粘度增高15例(100.0%),正常0例。50~69岁患者血浆粘度增高7例(38.9%),正常6例(33.3%),降低5例(27.8%);70~79岁患者血浆粘度增高6例(33.3%),正常12例(66.7%),降低0例;80~79岁患者血浆粘度增高4例(26.7%),正常11例(73.3%),降低0例。病例组50~69、70~79岁全血粘度增高患者全血粘度低切、全血粘度中切、全血粘度高切值均高于全血粘度正常患者及健康对照组,80~89岁全血粘度增高患者全血粘度低切、全血粘度中切、全血粘度高切值均高于健康对照组,差异有统计学意义(P<0.05);病例组50~69、70~79岁全血粘度正常患者与健康对照组全血粘度低切、全血粘度中切、全血粘度高切值对比,差异无统计学意义(P>0.05)。病例组50~69、70~79、80~89岁血浆粘度增高患者血浆粘度高于血浆粘度正常患者和健康对照组,差异有统计学意义(P<0.05);病例组50~69岁血浆粘度降低患者血浆粘度低于同期血浆粘度增高、正常患者及健康对照组,差异有统计学意义(P<0.05);病例组50~69、70~79、80~89岁血浆粘度正常患者血浆粘度与健康对照组比较,差异无统计学意义(P>0.05)。结论在心功能不全气虚血瘀证患者中,≥50岁中老年患者随着年龄的增加全血粘度呈升高趋势,血浆粘度趋于正常。Objective To investigate the changes of blood viscosity in patients with Qi deficiency and blood stasis syndrome of chronic cardiac insufficiency.Methods 51 patients with Qi stagnation and blood stasis syndrome of cardiac insufficiency were selected as the case group,and another 23 healthy physical subjects were selected as the healthy control group.Whole blood viscosity and plasma viscosity tests were performed in both groups.The whole blood viscosity and plasma viscosity of patients with Qi deficiency and blood stasis syndrome of chronic cardiac insufficiency in different age groups were analyzed,and the results of whole blood viscosity(whole blood low-shear viscosity,whole blood middle-shear viscosity,whole blood high-shear viscosity)and plasma viscosity testing were compared between the two groups.Results The whole blood viscosity was increased in 13 cases(72.2%)and normal in 5 cases(27.8%)in patients aged 50-69 years;increased in 14 cases(77.8%)and normal in 4 cases(22.2%)in patients aged 70-79 years;increased in 15 cases(100.0%)and normal in 0 case in patients aged 80-89 years.The plasma viscosity was increased in 7 cases(38.9%),normal in 6 cases(33.3%),and decreased in 5 cases(27.8%)in patients aged 50-69 years;increased in 6 cases(33.3%),normal in 12 cases(66.7%),and decreased in 0 case in patients aged 70-79 years;increased in 4 cases(26.7%),normal in 11 cases(73.3%),and decreased in 0 case in patients aged 80-79 years.In the case group,the whole blood low-shear viscosity,whole blood middle-shear viscosity,and whole blood high-shear viscosity were higher in patients with increased whole blood viscosity aged 50-69 and 70-79 years than those in patients with normal whole blood viscosity and healthy control group;the whole blood low-shear viscosity,whole blood middle-shear viscosity,and whole blood high-shear viscosity in patients with increased whole blood viscosity aged 80-89 years were higher than those in the healthy control group;the differences were statistically significant(P<0.05).There was no stati

关 键 词：心功能不全 气虚血瘀证 血粘度 

分 类 号：R259[医药卫生—中西医结合]