堇菜属植物的化学成分及药理作用研究进展  

Research progress on chemical constituents and pharmacological activities of Viola plants

作　　者：张敏 高优恒 李烨 毕雅琼 张春红 李旻辉 詹志来[4] ZHANG Min;GAO You-heng;LI Ye;BI Ya-qiong;ZHANG Chun-hong;LI Min-hui;ZHAN Zhi-lai(Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine,Hohhot O10020,China;Department of Pharmacy,Baotou Medical College,Baotou 014040,China;Inner Mongolia Autonomous Region Academy of Chinese and Mongolian Medicine,Hohhot O10010,China;National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]内蒙古自治区中医医院,内蒙古呼和浩特010020 [2]包头医学院药学院,内蒙古包头014040 [3]内蒙古自治区中蒙医药研究院,内蒙古呼和浩特010010 [4]中国中医科学院中药资源中心,北京100700

出　　处：《中国中药杂志》2023年第5期1145-1175,共31页China Journal of Chinese Materia Medica

基　　金：中央本级重大增减支项目(2060302)。

摘　　要：堇菜科堇菜属Viola植物全球现存500余种,约有111种在我国广泛分布,且药用历史悠久,品种繁多。笔者统计目前已从该属植物中共分离并鉴定410个化合物,涵盖黄酮类、萜类、苯丙素类、有机酸类、含氮类、甾醇类、糖类及其衍生物、挥发油类、环肽类等,药理作用主要涉及抗菌、抗炎、抗病毒、抗氧化、抗肿瘤等。该文系统综述了国内外堇菜属植物的化学成分和药理活性研究进展,为其进一步深入研究和临床应用提供科学依据。There are 500 species of Viola(Violaceae)worldwide,among which 111 species are widely distributed in China and have a long medicinal history and wide varieties.According to the authors′statistics,a total of 410 compounds have been isolated and identified from plants of this genus,including flavonoids,terpenoids,phenylpropanoids,organic acids,nitrogenous compounds,sterols,saccharides and their derivatives,volatile oils and cyclotides.The medicinal materials from these plants boast anti-microbial,anti-viral,anti-oxidant and anti-tumor activities.This study systematically reviewed the chemical constituents and pharmacological activities of Viola plants to provide a basis for further research and clinical application.

关 键 词：堇菜属 化学成分 药理作用 综述 

分 类 号：R284.1[医药卫生—中药学] R285[医药卫生—中医学]