2006—2021年重庆市疑似预防接种异常反应监测分析  

Analysis on the surveillance of adverse events following immunization in Chongqing from 2006 to 2021

作　　者：柏宁培 许濒月[1] 王青[1] BAI Ning-pei;XU Bin-yue;WANG Qing(Chongqing Center for Disease Control and Prevention,Chongqing 400042,China)

机构地区：[1]重庆市疾病预防控制中心,重庆400042

出　　处：《现代预防医学》2023年第9期1711-1716,共6页Modern Preventive Medicine

基　　金：重庆市公共卫生重点专科(学科)建设经费资助。

摘　　要：目的分析重庆市2006—2021年疑似预防接种异常反应(AEFI)分布情况,为评价重庆市预防接种安全性提供依据。方法通过AEFI个案监测系统和重庆市免疫规划信息管理系统收集2006年1月1日—2021年12月31日,重庆市报告的AEFI数据以及接种数据,采用描述性流行病学对监测数据进行统计分析。结果2006—2021年重庆市共报告AEFI个案20117例,总报告发生率为20.22/10万,2018年达到最高峰,为38.56/10万;其中一般反应发生率为16.47/10万、异常反应发生率为3.12/10万。AEFI的发生主要集中在4—9月,<1岁的占69.15%。结论重庆市2006—2021年AEFI报告发生率基本逐年上升,但从2018年开始有所下降,还需进一步加强监测,提高AEFI监测敏感性。Objective To analyze characteristics of adverse events following immunization(AEFI)in Chongqing from 2006 to 2021,and to provide a basis for evaluating the safety of vaccination.Methods The data of AEFI cases reported and vaccination from 2006 to 2021 were collected through China AEFI information management system and Chongqing Immunization Planning Information Management System for a descriptive epidemiological analysis.Results A total of 20117 AEFI cases were reported in Chongqing from 2006 to 2021,with a total reported incidence of 20.22/100000 doses and the peak of 38.56/100000 doses in 2018.The incidence of general reactions was 16.47/100000 doses,and the incidence of abnormal reactions was 3.12/100000 doses.Cases were concentrated in April to September,and 69.15%of cases in infants were less than 1 year old.Conclusion The reported incidence of AEFI in Chongqing increased year by year from 2006 to 2021,but it decreased from 2018.It is necessary to further strengthen surveillance and improve AEFI monitoring sensitivity.

关 键 词：疑似预防接种异常反应 监测 疫苗 

分 类 号：R186[医药卫生—流行病学]