北京市206例境外输入性新冠病毒感染者流行病学特征对比分析  

Comparative analysis of epidemiological characteristics of 206 imported COVID-19 cases in Beijing

作　　者：田寒梅[1] 徐露婷 张永[1] 王东[3] Tian Hanmei;Xu Luting;Zhang Yong;Wang Dong(Institute of Environmental Health,Beijing Center for Disease Prevention and Control,Beijing 100013,China;Institute for Health Education,Beijing Center for Disease Prevention and Control,Beijing 100013,China;Emergency Responding Office,Beijing Center for Disease Prevention and Control,Beijing 100013,China)

机构地区：[1]北京市疾病预防控制中心环境卫生所,100013 [2]北京市疾病预防控制中心健康教育所,100013 [3]北京市疾病预防控制中心应急办公室,100013

出　　处：《国际病毒学杂志》2023年第2期146-150,共5页International Journal of Virology

摘　　要：目的分析比较不同新型冠状病毒(SARS-CoV-2)变异株流行时期北京市境外输入性新型冠状病毒感染者的流行病学特征,为进一步做好"外防输入"的疫情防控工作提供数据支撑。方法将2021年10月1日至2022年2月28日由首都机场口岸入境的新型冠状病毒感染者分为2组,入境日期在2021年12月17日之前的为D组,之后的为O组,分析2组感染者在来源的国家/地区、发病特征和在院时间等方面的差异。采用WPS Office软件整理数据,应用R 4.0.2软件进行统计分析。结果共纳入新型冠状病毒感染者206例,其中D组53例,主要来自瑞典、奥地利等欧洲国家/地区,O组153例,主要来自中国香港地区和韩国等亚洲国家/地区。D组中普通型病例的比例(20.75%,11/53)较O组(10.46%,16/153)高,两组感染者分类情况的差异有统计学意义(χ^(2)=29.07,P<0.05)。D组入境至核酸首次阳性的时间间隔M(Q1,Q3)为3(1,7)d,较O组M(Q1,Q3)1(1,4)d长(Z=3.54,P<0.05),在入境后7 d内核酸首次阳性的比例O组(92.81%,142/153)较D组(75.47%,40/53)高,两组入境至核酸首次阳性的时间间隔的分布差异有统计学意义(P<0.05)。D组的在院时间M(Q1,Q3)为6(3,15)d,O组在院时间的M(Q1,Q3)为14(8,19)d,其差异有统计学意义(Z=-3.86,P<0.05)。结论Omicron变异株的潜伏期较Delta变异株短,感染Omicron变异株的大多数输入性感染者均能在入境后10 d内发现,感染者分型多为无症状和轻型,普通型病例的比例较低,但住院时间延长。Objective To compare the epidemiological characteristics of imported coronavirus disease 2019(COVID-19)cases in different epidemic periods of SARS-CoV-2 variant in Beijing,so as to provide scientific basis for the"Guarding Against Imported Cases"policy in the prevention and control of COVID-19.Methods The imported severe acute respiratory syndrome coronavirus 2(SARS-Co-2)infected patients from October 1,2021 to February 28,2022 who entering China from Beijing Capital International Airport were divided into two groups according to the entry dates before and after December 17,2021(group D and O).The differences in the origin countries/regions,epidemiological characteristics and hospitalization time between the two groups were analyzed.WPS Office software was used for data management and R 4.0.2 was used for statistical analysis.Results A total of 206 imported cases infected with SARS-CoV-2 were enrolled in the analysis,including 53 cases in group D who were mainly from European countries and regions such as Sweden and Austria,and 153 cases in the group O who were mainly from Asian countries and regions such as South Korea and Hong Kong Special Administrative Region.The proportion of moderate cases in group D(20.75%,11/53)was higher than that in group O(10.46%,16/153),and the differences in clinical typing between the two groups were statistically significant(χ^(2)=29.07,P<0.05).The median interval from the entry to the first positive nucleic acid detection(M(Q1,Q3))for group D was 3(1,7)days and longer than M(Q1,Q3)of 1(1,4)days in group O(Z=3.54,P<0.05).The proportion of the imported cases with the first positive nucleic acid detection within 7 days in group O(92.81%,142/153)was higher than that in group D(75.47%,50/53),and the difference in time interval distribution between the two groups was statistically significant(P<0.05).For time of hospitalization,M(Q1,Q3)in group D and group O were 6(3,15)and 14(8,19)days,respectively and the difference was statistically significant(Z=-3.86,P<0.05).Conclusions The incuba

关 键 词：新型冠状病毒感染 Omicron变异株 境外输入 流行病学特征 

分 类 号：R563.1[医药卫生—呼吸系统] R181.3[医药卫生—内科学]