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作 者:张博林[1] 吴义忠 李海军[1] 徐哲[1] 魏昊 ZHANG Bo-lin;WU Yi-zhong;LI Hai-jun;XU Zhe;WEI Hao(Clinieal Laboratary Department,Guangyuan Cental Hospital,Guangyuan,Sichuan,628000,China)
出 处:《中国初级卫生保健》2023年第3期42-45,共4页Chinese Primary Health Care
基 金:广元市科技局重点研发项目(20ZDYF0013)。
摘 要:目的:了解四川省广元市部分育龄妇女及婴幼儿TORCH感染情况,为优生优育提供相关信息。方法:选取2020年12月—2022年1月在广元市中心医院进行体检或产前筛查的育龄妇女(20~42岁)及婴幼儿为研究对象,排除其中患基础疾病者,共纳入育龄妇女1147名、婴幼儿164名,采用化学发光检测系统测定其血清中弓形虫(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)、单纯疱疹病毒I型(HSV I)和单纯疱疹病毒II型(HSV II)特异性抗体IgG和IgM。结果:1147名育龄妇女TORCH-IgG抗体阳性率分别为:CMV-IgG 95.90%,RV-IgG 85.00%,HSV I-IgG 23.89%,HSV II-IgG12.29%,Tox-IgG 6.45%。TORCH-IgM抗体阳性率分别为:CMV-IgM 1.74%,HSV II-IgM 1.13%,RV-IgM 0.52%,Tox-IgM0.44%,HSV I-IgM 0.08%。婴幼儿TORCH-IgG抗体阳性率分别为:CMV-IgG 83.53%,RV-IgG 70.12%,HSV I-IgG82.93%,HSV II-IgG 15.24%,Tox-IgG 7.32%。TORCH-IgM抗体阳性率分别为:CMV-IgM 26.83%,HSV II-IgM 1.22%,RV-IgM 1.22%,Tox-IgM 0,HSV I-IgM 0。结论:四川省广元市部分育龄妇女及婴幼儿存在一定的TORCH感染,针对育龄妇女及婴幼儿的TORCH监测非常有意义。OBJECTIVE To investigate the status of TORCH infection among women of childbearing age and young children in Guangyuan district of Sichuan,and to provide relevant information for prenatal and postnatal care.METHODS Chemiluminescence detection system was used to detect Toxoplasma gondii(TOX),Rubella virus(RV),Cytomegalo virus(CMV)and Herpes simplex virus typeⅠ(HSVⅠ)and typeⅡ(HSVⅡ)specific antibodies IgG and IgM in serum of women of childbearing age(1147 cases)and young children(164 cases)in Guangyuan district from December of 2020 to January of 2022.RESULTS The positive rate of TORCH-IgG antibodies in 1147 cases women of childbearing age:CMV IgG 95.90%,RV IgG 85.00%,HSVⅠ-IgG 23.89%,HSVⅡ-IgG 12.29%,and Tox-IgG 6.45%.The positive rates of TORCH-IgM antibody:CMV-IgM 1.74%,HSVⅡ-IgM 1.13%,RV-IgM0.52%,Tox-IgM 0.44%,and HSVⅠ-IgM 0.08%.The positive rates of TORCH-IgG antibodies in 164 cases young children:CMV IgG 83.53%,RV IgG 70.12%,HSVⅠ-IgG 82.93%,HSVⅡ-IgG 15.24%,and Tox-IgG 7.32%.The positive rates of TORCH-IgM antibody CMV-IgM 26.83%,HSVⅡ-IgM 1.22%,RV-IgM 1.22%,Tox-IgM 0,and HSVⅠ-IgM 0.CONCLUSION There is a certain TORCH infection rate among women of childbearing age and young children in Guangyuan district,Sichuan Province.TORCH monitoring is very meaningful to women of childbearing age and young children.
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