南昌地区某院就诊患者γ-干扰素释放试验的应用价值研究  

Study on Application Value of Interferon-γ Release Assay in Patients in a Hospital in Nanchang

作　　者：杨小军[1] 金桂林 沈凤鸣 彭国华[2] YANG Xiaojun;JIN Guilin;SHEN Fengming;PENG Guohua(Affiliated Hospital of Jiangxi University of Chinese Medicine,Nanchang;Nanchang Center for Disease Control and Prevention,Nanchang,Jiangxi Province,330006)

机构地区：[1]江西中医药大学附属医院 [2]南昌市疾病预防控制中心,南昌330006

出　　处：《江西医药》2023年第3期269-270,280,共3页Jiangxi Medical Journal

基　　金：江西省卫生计生委中医药科研基金课题,编号2018A383。

摘　　要：目的了解江西省南昌地区某院就诊患者γ-干扰素释放试验(IGRA)检测结核分枝杆菌潜伏感染流行病学特征。方法收集江西省南昌地区某院2017年1月至2020年12月来院就诊的2561例患者血液,用γ干扰素释放试验检测患者潜在感染状况。结果就诊患者IGRA阳性率为39.55%(1013/2561),不同年份患者之间IGRA阳性率比较,差异无统计学意义(χ^(2)=4.775,P>0.05),不同性别、不同年龄组患者之间IGRA阳性率比较,差异有统计学意义(χ^(2)=9.442,χ^(2)=18.487,均P<0.05)。结论南昌地区某院就诊患者结核杆菌潜伏感染相对较高,提示应加强人员监测力度,提高结核分枝杆菌潜伏感染的早期诊断率。Objective Studying epidemiological features of latent infection of mycobacterium tuberculosis on the basis of Interferon-γRelease Assay(IGRA)in patients in a hospital in Nanchang.Methods Collecting blood from 2561 patients who visited a hospital in Nanchang,Jiangxi Province from January 2017 to December 2020;detecting the potential infection status of patients by IGRA.Results The IGRA positivity rate of patients visiting the hospital was 39.55%(1013/2561);no statistical difference was discovered in the IGRA positivity rate among patients of different years,(χ^(2)=4.775,P>0.05).statistical difference was discovered in the IGRA positivity rate among patients of different genders and age groups(χ^(2)=9.442,χ^(2)=18.487,P<0.05).Conclusion A relatively high incidence of latent infection of Mycobacterium tuberculosis is observed in a hospital in Nanchang.This result suggests that health surveillance of residents should be strengthened to improve the early diagnosis of latent infection of Mycobacterium tuberculosis.

关 键 词：γ-干扰素释放试验(IGRA) 结核杆菌 潜伏感染 

分 类 号：R521.7[医药卫生—内科学]