非负重运动锻炼对糖尿病足溃疡病人影响的系统评价  

Effect of non-weight bearing exercise on diabetic foot ulcer patients:a systematic review

作　　者：陶静[1] 刘清华 胡鹏 张静[1] 龚亚 刘晓 TAO Jing;LIU Qinghua;HU Peng;ZHANG Jing;GONG Ya;LIU Xiao(Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei 430030 China)

机构地区：[1]华中科技大学同济医学院附属同济医院,湖北430030

出　　处：《循证护理》2023年第10期1745-1752,共8页Chinese Evidence-Based Nursing

摘　　要：目的:系统评价非负重运动锻炼在糖尿病足溃疡病人中应用效果,为糖尿病足运动干预提供循证依据。方法:计算机检索PubMed、the Cochrane Library、EMbase、Web of Science、中国知网、万方数据库收录的关于非负重运动锻炼在糖尿病足溃疡病人中应用的随机对照试验,检索时限从建库到2022年8月31日。由2名研究人员进行筛选文献、提取资料和评价文献质量,采用RevMan 5.3软件进行Meta分析。结果:共纳入15篇随机对照试验,涉及1296例糖尿病足病人。Meta分析结果显示,非负重运动锻炼可以改善糖尿病足溃疡病人的伤口愈合率[RR=2.76,95%CI(2.00,3.80),P<0.00001],改善病人的踝肱指数(ABI)[RR=0.07,95%CI(0.04,0.10),P<0.0001];两组运动时不良事件发生率比较,差异无统计学意义[RR=0.76,95%CI(0.54,1.09),P=0.14];非负重运动锻炼对血糖相关指标和生活质量的影响尚不明确。结论:现有证据表明,非负重运动锻炼对糖尿病足溃疡病人有较好的临床结局,可以提高病人的伤口愈合率,改善病人的ABI。但纳入的研究在质量和数量上有所限制,需要更多高质量和大样本的研究对此结论进行验证。Objective:To systematically evaluate the effect of non-weight bearing exercise in patients with diabetes foot ulcer,and to provide evidence-based evidence for diabetes foot exercise intervention.Methods:The randomized controlled trials on the application of non weight bearing exercise in patients with diabetes foot ulcer were retrieved from PubMed,the Cochrane Library,EMbase,Web of Science,CNKI,WanFang Database.The search period was from the establishment of the database to August 31,2022.Literature screening,data extraction and literature quality evaluation were conducted by two researchers.RevMan 5.3 software was used for Meta-analysis.Results:A total of 15 randomized controlled trial articles were included,involving 1296 diabetic foot patients.Meta-analysis showed that non-weight-bearing exercise could improve the wound healing rate[RR=2.76,95%CI(2.00,3.80),P<0.00001]and ABI[RR=0.07,95%CI(0.04,0.10),P<0.0001]of diabetic foot ulcer patients.There was no significant difference in the incidence of adverse events during exercise between the two groups[RR=0.76,95%CI(0.54,1.09),P=0.14].The effect of non-weight bearing exercise on blood glucose related indicators and quality of life was unclear.Conclusion:Available evidence suggests that non-weight bearing exercise has better clinical outcomes in diabetic foot ulcers,improves the rate of wound healing and improves ABI.The studies included in this study are limited in quality and quantity,so more high-quality and large-sample studies are needed to verify this conclusion.

关 键 词：糖尿病足溃疡 非负重运动锻炼 伤口愈合率 系统评价 循证护理 

分 类 号：R473.5[医药卫生—护理学]