小儿肺系病证核心信息特征的研究  

Study on Characteristics of Core Information of Pulmonary Diseases in Children

作　　者：张柯欣[1] 常一川 王雪峰[2] ZHANG Kexin;CHANG Yichuan;WANG Xuefeng(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《中华中医药学刊》2023年第4期96-99,I0027,共5页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(82274580,8177150255);辽宁省教育厅科研项目(LJKZ0894、L202059、教2021-549);辽宁中医药大学项目(2021自然科学类重点-18、LNZYJG2020135、KGCXJS20200915002、X202110162001S、X202110162006S)。

摘　　要：探讨小儿肺系病证核心信息特征的表征及分析方法。“同病异证”与“异病同证”一直以来是中医学所独有的特色理念,以小儿肺炎证候学为例,“同病异证”体现为风寒闭肺证、风热闭肺证、痰热闭肺证、湿热闭肺证、毒热闭肺证、阴虚肺热证等,以上证型的病理机制中存在着递进与关联。同时,在病证的演变过程中患者的病理生理指标也会相应地发生变化,能够客观反映这些变化的临床常用指标则可以用来构造该病证知识模型的应用域和客观观察域。根据这些信息特征建立的数学模型可以展现此种变化内外机制,揭示中医病机证候特征从量变到质变的复杂关系。按照这一理论,针对儿童肺系疾病中常见的“异病同证”:上呼吸道感染、支气管炎、支气管肺炎,将此3种疾病同在风热证阶段的核心指标组合在病证指标矩阵中,并以此设计出同证病种同心环图,确立不同的疾病之间核心指标的分布,进而设计了病证指标耦合图,用来分析同证不同病种的核心信息指标的耦合情况,探究病证指标分析与图论计算相关联的研究方法。阐明针对此种信息特征指标计算所需要的核心信息病例报告表的定义及设计理念。This paper discussed the characterization and analysis methods of the core information characteristics of pulmonary syndrome in children.“Same disease with different syndromes”and“different diseases with the same syndrome”have always been the unique characteristic concepts of traditional Chinese medicine.Taking pediatric pneumonia syndrome as an example,“same disease with different syndromes”is embodied in wind-cold closing lung syndrome,wind-heat closing lung syndrome,phlegm-heat closing lung syndrome,damp-heat closing lung syndrome,toxin-heat closing lung syndrome,Yin deficiency and lung heat syndrome and so on.There is a progressive and correlation in the pathological mechanism of the above syndrome types.At the same time,in the process of disease evolution,the pathophysiological indexes of patients will change accordingly.The commonly used clinical indexes that can objectively reflect these changes can be used to construct the application domain and objective observation domain of the disease syndrome knowledge model.The mathematical model based on these information characteristics can show the internal and external mechanism of this change and reveal the complex relationship between the characteristics of TCM pathogenesis and syndrome from quantitative change to qualitative change.According to this theory,aiming at“different diseases with the same syndrome”in children's lung diseases such as upper respiratory tract infection,bronchitis and bronchopneumonia,this paper combined the core indicators of these three diseases in the stage of wind-heat syndrome in the disease syndrome index matrix,and designed the concentric ring diagram of the same disease type to establish the distribution of core indicators among different diseases.Then the disease syndrome index coupling diagram was designed to analyze the coupling of core information indexes of different diseases with the same syndrome,and explored the research methods related to disease syndrome index analysis and graph theory calculation.It cl

关 键 词：小儿肺系病证 信息特征 病证指标矩阵 病证指标耦合 核心信息病例报告表 

分 类 号：R259.63[医药卫生—中西医结合]