桃红四物汤口服合清热解毒利湿方溻渍治疗下肢丹毒的临床研究  

Clinical Study on Treatment of Erysipelas in Lower Limbs with Taohong Siwu Decoction(桃红四物汤)Orally Combined with Qingre Jiedu Lishi Decoction(清热解毒利湿方)for Waterlogging Therapy

作　　者：申朝霞 井西宽 陈元 SHEN Zhaoxia;JING Xikuan;CHEN Yuan(Lianyungang Hospital of Traditional Chinese Medicine,Lianyungang 222000,Jiangsu,China)

机构地区：[1]连云港市中医院,江苏连云港222000

出　　处：《中华中医药学刊》2023年第4期202-205,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：江苏省卫生健康委员会面上项目(H2018091)。

摘　　要：目的观察桃红四物汤口服合清热解毒利湿方溻渍对下肢丹毒的疗效与作用。方法以随机数字表法将62例下肢丹毒患者分为对照组(31例,37患侧)和观察组(31例,38患侧)。对照组采用常规治疗(抗生素静滴+硫酸镁溶液外敷+抬高患肢休息),观察组在上述疗法的基础上予以桃红四物汤口服+清热解毒利湿方溻渍。对比两组青霉素使用率和使用量,治疗前后红肿面积,临床疗效,治疗前后血白细胞计数(WBC)、中性粒细胞百分比(N%)、血清C反应蛋白(CRP)水平,不良反应和复发率。结果两组青霉素使用率和使用量对比差异均无统计学意义(P>0.05);两组治疗后红肿面积均缩小,且治疗后观察组红肿面积小于对照组,上述差异均有统计学意义(P<0.05);两组临床疗效总有效率差异均有统计学意义(P<0.05),且观察组总有效率高于对照组(P<0.05);治疗后两组血WBC、N%、血清CRP水平均下降(P<0.05),且观察组均低于对照组(P<0.05);两组不良反应发生率和6个月内复发率差异均无统计学意义(P>0.05)。结论桃红四物汤口服合清热解毒利湿方溻渍治疗下肢丹毒可缩小红肿面积,增强疗效,减轻炎症反应,且安全,远期疗效好。Objective To observe the effect and role of Taohong Siwu Decoction(桃红四物汤)orally combined with Qingre Jiedu Lishi Decoction(清热解毒利湿方)for waterlogging therapy in patients with erysipelas in lower limbs.Methods Sixty-two patients with erysipelas in lower limbs were divided into control group(31 cases,37 limbs)and observation group(31 cases,38 limbs)by a random digital table.The control group was treated with routine western medicine(antibiotic intravenous drip+magnesium sulfate solution external application+elevation of the affected limb rest),while the observation group was treated with Taohong Siwu Decoction orally+Qingre Jiedu Lishi Decoction for waterlogging therapy on the basis of the above treatment.The usage rates and dosage of penicillin between the two groups were compared.Before and after treatment,the area of redness and swelling,clinical efficacy,white blood cell count(WBC),neutrophil percentage(N%)and serum C-reactive protein(CRP)before and after treatment,adverse reactions and recurrence rates were compared.Results There were no significant differences in the usage rates or dosage of penicillin between the two groups(P>0.05).The area of redness and swelling in the two groups after treatment reduced,and that in the observation group was lower than that in the control group with statistically significant differences(P<0.05).There were significant differences in the clinical efficacy distribution and total effective rates between the two groups(P<0.05),and the total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the levels of blood WBC,N%and serum CRP in the two groups decreased(P<0.05),and the levels in the observation group were lower than those in the control group(P<0.05).There were no significant differences in the incidences of adverse reactions or the recurrence rates within 6 months between the two groups(P>0.05).Conclusion Taohong Siwu Decoction orally combined with Qingre Jiedu Lishi Decoction for waterlogging ther

关 键 词：桃红四物汤 清热解毒利湿方 下肢丹毒 中西医结合 

分 类 号：R755.953.5[医药卫生—皮肤病学与性病学]