自拟降糖方治疗2型糖尿病胃肠湿热证临床观察  

作　　者：陆姗姗 徐静波 楼雨沁 蒋旭宏[1] 

机构地区：[1]浙江中医药大学,310053

出　　处：《浙江临床医学》2023年第4期562-564,共3页Zhejiang Clinical Medical Journal

摘　　要：目的分析2型糖尿病胃肠湿热证患者接受自拟降糖方治疗的临床疗效。方法取2022年1月至2023年2月就诊的2型糖尿病胃肠湿热证患者80例,将盐酸二甲双胍治疗的40例患者纳入对照组,增加使用自拟降糖方治疗的40例患者纳入观察组,分析两组临床疗效、BMI、血糖、血脂类指标、中医证候积分、糖尿病特异性生存质量量表(DSQL)评分。结果观察组总有效率100%,与对照组20%比较差异有统计学意义(P<0.05)。改善BMI程度方面,观察组优于对照组(P<0.05)。改善血糖指标方面,两组均能有效降低空腹血糖(FPG)、餐后2 h血糖(PBG)、糖化血红蛋白(HbA1c)(P<0.05),且观察组优于对照组(P<0.05)。改善血脂指标方面,观察组总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)与治疗前比较,有明显改善(P<0.05),且观察组优于对照组(P<0.05)。经治疗后观察组中医证候积分、DSQL评分均较前明显改善(P<0.05),且观察组优于对照组(P<0.05)。结论对2型糖尿病胃肠湿热证患者在常规治疗基础上加用自拟降糖方,患者血糖、血脂指标得以有效控制的同时,胃肠湿热证也得以控制,生活质量评分较前提高,值得推广。Objective To analyze the clinical efficacy of Hetang Granule in patients with type 2 diabetes mellitus with gastrointestinal damp-heat syndrome.Methods 80 patients with gastrointestinal damp heat syndrome of type 2 diabetes who went to hospital from January 2022 to February 2023 were selected as the subjects,40 patients who received conventional drug treatment were included in the control group,and 40 patients who increased the use of Hetang Granule were included in the observation group.The clinical efficacy,body mass index(BMI),blood glucose,lipid indicators,Traditional Chinese Medicine(TCM)syndrome score,and DSQL score of the two groups were analyzed.Results The total effective rate of patients in the observation group was 100.00%,compared with 20.00%in the control group.The data difference between the two groups was statistically significant(P<0.05).In terms of improving BMI,the observation group was better than the control group(P<0.05).In terms of improving blood glucose related indicators,both groups could effectively reduce FPG,PBG and HbA1c(P<0.05),and the observation group was superior to the control group(P<0.05).In terms of improving blood-lipid related indexes,TC,TG,HDL-C and LDL-C in the observation group were significantly improved compared with those before the treatment(P<0.05),and the observation group was superior to the control group(P<0.05).After the treatment,the TCM syndrome score and DSQL score of the observation group were significantly improved(P<0.05),and the observation group was superior to the control group(P<0.05).Conclusion For patients with type 2 diabetes with gastrointestinal damp-heat syndrome,adding Hetang Granule on the basis of conventional treatment,the patient's blood sugar and blood lipid indicators can be effectively controlled,and the gastrointestinal damp-heat syndrome can also be controlled,and the quality of life score is improved compared with before,which is worthy of promotion.

关 键 词：自拟降糖方 2型糖尿病 胃肠湿热证 糖脂代谢 临床疗效 

分 类 号：R587.1[医药卫生—内分泌] R57[医药卫生—内科学]