左室压力-应变环技术评估单纯性肥胖症患者左室收缩功能  

Evaluation of left ventricular systolic function in patients with simple obesity by left ventricular pressure-strain loop technology

作　　者：崔荣荣 冯婷华 薛继平 CUI Rongrong;FENG Tinghua;XUE Jiping(Department of Ultrasound,Shanxi Bethune Hospital,Taiyuan 030032,China)

机构地区：[1]山西白求恩医院、山西医学科学院同济山西医院、山西医科大学附属第三医院超声科,太原市030032

出　　处：《临床超声医学杂志》2023年第5期390-394,共5页Journal of Clinical Ultrasound in Medicine

摘　　要：目的应用左室压力-应变环(LVPSL)技术评估单纯性肥胖症患者左室心肌收缩功能。方法收集我院减重代谢外科门诊及住院的单纯性肥胖症患者64例,根据体质量指数(BMI)将其分为超重组(BMI 24~28 kg/m^(2))和肥胖组(BMI≥28 kg/m^(2)),每组各32例;另选同期年龄、性别与之相匹配的非肥胖健康志愿者46例作为对照组(BMI<24 kg/m^(2))。各组均行斑点追踪技术获取整体纵向应变(GLS),LVPSL技术获取左室心肌做功参数,包括整体做功指数(GWI)、整体有用功(GCW)、整体无用功(GWW)及整体做功效率(GWE),比较各组上述参数的差异;分析左室心肌做功参数与GLS、BMI,以及GLS与BMI的相关性。结果与对照组比较,超重组和肥胖组GLS、GWI、GCW均减低,GWW增加,差异均有统计学意义(均P<0.05);与超重组比较,肥胖组GLS、GWI、GCW均减低、GWW增加,差异均有统计学意义(均P<0.05)。各组GWE比较差异无统计学意义。相关性分析显示,GLS与GWI、GCW均呈正相关(r=0.875、0.833,均P<0.001),与GWW呈负相关(r=-0.879,P<0.001),与GWE无相关性;GLS、GWI、GCW与BMI均呈负相关(r=-0.861、-0.744、-0.763,均P<0.05),GWW与BMI呈正相关(r=0.897,P<0.05),GWE与BMI无相关性。结论LVPSL技术可早期定量评估单纯性肥胖症患者左室收缩功能,且BMI越高,左室收缩功能受损越严重。Objective To evaluate the left ventricular systolic function in patients with simple obesity by left ventricular pressure-strain loop(LVPSL)technology.Methods A total of 64 patients with simple obesity were collected from the outpatients and inpatients of bariatric metabolic surgery in our hospital.According to body mass index(BMI),all patients were divided into overweight group(BMI 24~28 kg/m^(2))and obese group(BMI≥28 kg/m^(2)),with 32 cases in each group,and 46 healthy volunteers with the same age and gender were collected as the control group(BMI<24 kg/m^(2)).The global longitudinal strain(GLS)were obtained by speckle tracking technique,and the myocardial work parameters were obtained by LVPSL technique,including the global work index(GWI),global constructive work(GCW),global waste work(GWW)and global work efficiency(GWE).The differences of above parameters among the three groups were compared,and the correlation between myocardial work parameters with GLS and BMI,GLS and BMI were analyzed.Results Compared with the control group,GLS,GWI and GCW were decreased in overweight groups and obese groups,while GWW was increased,the differences were statistically significant(all P<0.05).Compared with the overweight group,GLS,GWI and GCW decreased and GWW increased in obese groups,the differences were statistically significant(all P<0.05).There was no significant differences in GWE among the groups.Correlation analysis showed that GLS was positively correlated with GWI and GCW(r=0.875,0.833,both P<0.001),while negatively correlated with GWW(r=-0.879,P<0.001),and no correlated with GWE.GLS,GWI and GCW were negatively correlated with BMI(r=-0.861,-0.744,-0.763,all P<0.05),while GWW was positively correlated with BMI(r=0.897,P<0.05),and GWE was not correlated with BMI.Conclusion LVPSL technology can quantitatively evaluate left ventricular systolic function in obese patients in the early stage,and the higher the BMI,the more severe the damage of left ventricular systolic function.

关 键 词：超声心动描记术 压力-应变环 单纯性肥胖症 心肌做功 收缩功能 心室 左 

分 类 号：R540.45[医药卫生—心血管疾病] R589.2[医药卫生—内科学]