中医药辨证治疗癫痫的研究进展  

Epilepsy Treated by Traditional Chinese Medicine Based on Syndrome Differentiation:A Review

作　　者：苏发智 孙延平[1] 白晨曦 张文森 杨炳友[1] 王秋红[1,2] 匡海学 SU Fazhi;SUN Yanping;BAI Chenxi;ZHANG Wensen;YANG Bingyou;WANG Qiuhong;KUANG Haixue(Key Laboratory of Basic and Application Research of Beiyao,Ministry of Education,Heilongjiang University of Chinese Medicine,Harbin 150040,China;School of Traditional Chinese Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China)

机构地区：[1]黑龙江中医药大学教育部北药基础与应用研究重点实验室,哈尔滨150040 [2]广东药科大学中药学院,广州510006

出　　处：《中国实验方剂学杂志》2023年第11期200-211,共12页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家重点研发计划中医药现代化研究重点专项(2018YFC1707100);国家中医药管理局中医药传承与创新“百千万”人才工程-岐黄工程首席科学家支持项目(国中医药人教函[2021]7号);国家中医药管理局中医药传承与创新“百千万”人才工程(岐黄工程)岐黄学者支持项目(国中医药人教函[2018]284号);2022年全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号);第七批全国老中医药专家学术经验继承工作项目(国中医药人教函[2022]76号);黑龙江省“头雁”团队支持项目(黑龙江省头雁行动领导小组文件[2019]5号)。

摘　　要：癫痫是一种表现为痫性发作的慢性脑部疾病,是临床上最常见的神经系统疾病之一,具有反复发作性、短暂性、难治性的特征。临床上治疗癫痫以西药为主,但是其产生的不良反应较大,会不同程度地导致消化系统、中枢神经系统、造血系统、泌尿系统和肝功能异常,不利于患者长期服用。中医药治疗癫痫采用辨证论治的方式,在改善患者证候的基础上又能避免西药治疗的不良反应。通过检索国内外中医药治疗癫痫的文献发现,中医辨证常以痰、瘀、风、虚辨证,治法以针刺、穴位埋线、艾灸、中药单体、中药药对及复方汤剂为主。中医药采用多种治法缓解癫痫发作的程度、减少发作的次数,发挥着多途径、多环节、全面性治疗癫痫的重要作用。该文综合整理了中医药治疗癫痫的临床经验,系统阐述了中医药治疗癫痫的经典治法及思路,并在此基础上深入地探讨了中药治疗癫痫的作用机制,旨在为临床制定合理的个体化治疗癫痫方案提供理论基础,为中医药更加有效地治疗癫痫提供多元化的思路。Epilepsy is a chronic brain disease characterized by seizures,and is one of the most common nervous system diseases in clinic practice with the recurrent,transient,and refractory characteristics.Clinically,western medicine therapy is mainly adopted in the treatment of epilepsy,but it is not conducive to long-term use for patients on account of severe side effects,which can result in abnormalities in the digestive system,central nervous system,hematopoietic system,urinary system,and liver function to varying degrees.Syndrome differentiation is usually used for the treatment of epilepsy by traditional Chinese medicine(TCM),which can avoid the side effects of western medicine treatment on the basis of improving patients'syndromes.The literature on TCM in the treatment of epilepsy in China and abroad indicates that the syndrome differentiation in TCM is often based on phlegm,blood stasis,wind,and deficiency,and the treatment methods include acupuncture,acupoint catgut embedding,moxibustion,Chinese medicine monomer,drug pair,and compound decoction.The various treatments of TCM play an important role in the comprehensive treatment of epilepsy through multiple channels and links,such as reducing the degree and number of seizures.This paper comprehensively summarized the clinical experience of TCM in the treatment of epilepsy,systematically expounded various treatment methods and ideas of TCM in the treatment of epilepsy,and deeply discussed the mechanism of TCM in the treatment of epilepsy,aiming to provide a theoretical basis for the clinical formulation of a reasonable individualized treatment plan for epilepsy and diversified ideas for the more effective treatment of epilepsy by TCM.

关 键 词：癫痫 辨证 中医药治疗 临床经验 作用机制 

分 类 号：R2-0[医药卫生—中医学] R22R285.5R284R2-031R742.1