注射用血栓通(冻干)临床应用专家共识制定中的文献预检索  

Literature pre-search in the development of expert consensus on clinical application of Xueshuantong for injection(lyophilized)

作　　者：宋歌亮 杜雪晨 庞稳泰 刘春香 SONG Ge-liang;DU Xue-chen;PANG Wen-tai;LIU Chun-xiang(Evidence-Based Medicine Center,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学循证医学中心,天津301617

出　　处：《现代药物与临床》2023年第4期951-961,共11页Drugs & Clinic

基　　金：天津市高等学校“创新团队培养计划”(TD13-5047)。

摘　　要：目的 通过注射用血栓通(冻干)及同类中药注射剂文献情况,找准临床定位,并为正式文献检索提供思路。方法在参与注射用血栓通(冻干)临床应用专家共识的编制工作时,按照中华中医药学会标准化办公室的标准流程,将“文献预检索”运用在构建临床问题步骤中,对注射用血栓通(冻干)及同类中药注射剂文献发表情况、注射用血栓通(冻干)及相同有效成分中药系统评价/Meta分析、注射用血栓通(冻干)说明书临床适应证的相关指南/专家共识中成药纳入情况及相关指南推荐用药方案情况4方面进行文献预检索。结果 注射用血栓通(冻干)发表的文献总量与同类中成药相比较少,在文献发表方面无明显优势。建议结合权威专家访谈和大样本的临床调研,获取权威专家的用药经验及临床医生最广泛关注的用药问题,以弥补证据不足情况。结论 对注射用血栓通(冻干)文献预检索在构建临床问题中的应用和实践做重点介绍,以期为中成药临床应用专家共识工作的开展提供借鉴。Objective Through the literature of Xueshuantong for injection(freeze-dried) and similar traditional Chinese medicine injections,the clinical positioning was identified,and the ideas for formal literature retrieval were provided.Methods When participating in the preparation of expert consensus on the clinical application of Xueshuantong for injection(freeze-dried),according to the standard process of Standardization Office of China Association of Traditional Chinese Medicine,“literature pre-search” was applied in the process of constructing clinical problems.For injection via blood clots(lyophilization) and similar Chinese medicine injection literatures published results,for injection via blood clots(lyophilization) and the same active ingredients evaluation/Meta analysis of traditional Chinese medicine system,injection with thrombosis(lyophilization) instruction clinical indications related guide/expert consensus proprietary Chinese medicine into the situation and related guidelines recommend regimen in four aspects,such as literature retrieval.Results Xueshuantong for injection(freeze-dried) has less literature publication than similar proprietary Chinese medicine,so it has no obvious advantage in literature publication.It is suggested to combine authoritative expert interviews and large sample clinical research to obtain the medication experience of authoritative experts and the medication problems most widely concerned by clinicians,so as to make up for the lack of evidence.Conclusions The application and practice of Xueshuantong for injection(freeze-dried) literature pre-search in the construction of clinical problems are mainly introduced,in order to provide reference for the development of expert consensus on clinical application of proprietary Chinese medicine.

关 键 词：注射用血栓通(冻干) 文献预检索 专家共识 中药系统评价 临床适应证 

分 类 号：R972[医药卫生—药品]