无诱因静脉血栓栓塞症患者潜在恶性肿瘤的筛查  

Screening for occult cancer in patients with unprovoked venous thromboembolism

作　　者：乔力松[1] 许小毛[1] Qiao Lisong;Xu Xiaomao(Division of Respiratory and Critical Care Medicine,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,China,Beijing 100730,China)

机构地区：[1]北京医院呼吸与危重症医学科、国家老年医学中心、中国医学科学院老年医学研究院,北京100730

出　　处：《中华结核和呼吸杂志》2023年第5期498-502,共5页Chinese Journal of Tuberculosis and Respiratory Diseases

基　　金：国家重点研发计划(2016YFC0905602);国家科技支撑计划(2011BAI11B17)。

摘　　要：静脉血栓栓塞症(VTE)包括深静脉血栓形成和肺栓塞,是第三大最常见的心血管疾病。无诱因VTE常常是恶性肿瘤的首发表现,有研究表明,高达10%的无诱因VTE患者在确诊后1年内发现恶性肿瘤。对无诱因VTE患者进行肿瘤筛查,使潜在肿瘤患者得到早期诊断、早期治疗,理论上可降低肿瘤相关患病率和病死率。本文就VTE患者潜在肿瘤的流行病学、目前筛查策略的循证医学研究、肿瘤的危险因素及风险评估模型等进行综述。Venous thromboembolism(VTE),which includes deep vein thrombosis and pulmonary embolism,is the third most common cardiovascular disease.Unprovoked VTE can be the initial presentation of occult cancer.Up to 10%of patients with unprovoked VTE are diagnosed with cancer within a year.Cancer screening in patients with unprovoked VTE is beneficial for early cancer diagnosis and treatment,which may theoretically reduce cancer-related morbidity and mortality.The epidemiology of occult cancer in patients with unprovoked VTE,screening strategies originated from evidence-based medicine,risk factors of cancer and different models of risk assessment are reviewed in this article.

关 键 词：深静脉血栓形成 静脉血栓栓塞症 肿瘤筛查 筛查策略 心血管疾病 风险评估模型 恶性肿瘤 循证医学研究 

分 类 号：R543.6[医药卫生—心血管疾病] R730.4[医药卫生—内科学]