人脱落乳牙牙髓干细胞治疗非口腔疾病的研究进展  

Recent Developments in Stem Cells from Human Exfoliated Deciduous Teeth in the Treatment of Non-oral Diseases

作　　者：蒋志寒 徐凌[1] JIANG Zhihan;XU Ling(Department of Pulmonary and Critical Care Medicine,the Sixth People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200233,China)

机构地区：[1]上海交通大学附属第六人民医院呼吸与危重症医学科,上海市200233

出　　处：《中国全科医学》2023年第24期3067-3073,共7页Chinese General Practice

基　　金：上海吴孟超医学科技基金(JJHXM-2019038)。

摘　　要：人脱落乳牙牙髓干细胞(SHEDs)作为一类具有较强增殖能力且能够多向分化的牙源性干细胞,易于获取且符合伦理要求,在干细胞治疗中具有很大潜力。目前关于SHEDs在非口腔疾病中的治疗作用缺乏阐述,本文就SHEDs在神经系统、消化系统、心血管系统、泌尿系统、免疫系统、内分泌系统及呼吸系统疾病中的最新治疗进展做一综述,以期为SHEDs在非口腔疾病中的临床应用提供参考。Stem cells from human exfoliated deciduous teeth(SHEDs)are odontogenic stem cells with strong proliferation ability and multilineage differentiation potential.Due to their easy accessibility and limited ethical concerns,SHEDs have great potential in stem cell therapy.There is still a lack of literature on SHEDs in the treatment of non-oral diseases.This article reviews the latest developments in the use of SHEDs to treat diseases of the nervous,digestive,cardiovascular,urinary,immune,endocrine and respiratory systems.This review will inform the clinical application of SHEDs in non-oral diseases.

关 键 词：干细胞 人脱落乳牙牙髓干细胞 非口腔疾病 综述 

分 类 号：R329.24[医药卫生—人体解剖和组织胚胎学]