弱激光对正畸隐形矫正患者牙周炎症和牙根吸收的影响  

Effect of Low Level Laser Therapy on Periodontal Inflammation and Root Re⁃sorption in Orthodontic Patients with Invisibility

作　　者：张婉君 孔中楠 马永平[1] 崔敬雅 杨茜 马文盛 ZHANG Wanjun;KONG Zhongnan;MA Yongping;CUI Jingya;YANG Qian;MA Wensheng(Department of Stomatology,the Second Hospital of Baoding,Baoding 071000,China)

机构地区：[1]保定市第二医院口腔科,保定市071000

出　　处：《中国激光医学杂志》2023年第2期68-73,120,共7页Chinese Journal of Laser Medicine & Surgery

基　　金：河北省科技计划项目(212777154)。

摘　　要：目的观察弱激光(low level laser therapy,LLLT)对正畸隐形矫正患者牙周炎症及牙根吸收的影响。方法选择2019年6月至2021年12月,接受正畸隐形矫正患者80例,按照随机数字表分为对照组和观察组,每组患者40例。对照组和观察组患者牙齿均采用无托槽隐形矫治技术进行隐形矫正,观察组患者牙齿同时给予LLLT干预,每个位置照射功率密度80 mW/cm^(2),照射时间30 s,每日1次,共治疗1周。于矫正前(T0)、矫正1 d、4 d及矫正7 d(T1)采用视觉模拟评分法(visual analogue score,VAS)评估患者牙周疼痛程度;比较两组患者T0、T1牙周状态菌斑指数(plaque index,PLI)和探诊出血(bleeding on probing,BOP);分析龈沟液中白细胞及中性粒细胞数量改变;检测龈沟液炎症因子包括肿瘤坏死因子(tumor necrosis factor,TNF)-α、白细胞介素(interleukin,IL)-1β水平变化。结果T0时,对照组和观察组患者VAS差异无统计学意义(P>0.05),而观察组患者矫正1 d、4 d、7 d时VAS显著低于对照组患者(P<0.05);对照组和观察组患者T0时牙BOP、PLI,龈沟液白细胞、中性粒细胞数量及肿瘤坏死因子TNF-α、白细胞介素IL-1β水平,牙根长度均无显著性差异(P>0.05);相比于T0,观察组和对照组患者T1时牙龈BOP、PLI,龈沟液白细胞、中性粒细胞数量及TNF-α、IL-1β水平显著增加,牙根长度显著减少(P<0.05),而观察组患者T1时牙龈BOP、PLI,龈沟液白细胞、中性粒细胞数量及TNF-α、IL-1β水平显著低于对照组,牙根长度显著长于对照组(P<0.05)。结论正畸隐形矫正过程给予弱激光干预有助于抑制牙周炎症反应及牙根吸收,值得临床推广。Objective To observe the effects of low level laser therapy(LLLT)on periodontal inflammation and root resorption in orthodontic patients.Methods Totally 80 patients given orthodontic invisible correction over the period from Jun.2019 to Dec.2021 were selected and divided into a control group and an observation group with random number table,40 patients in each group.The teeth of both groups were treated with bracket-free invisible orthodontic technique for invisible correction.The teeth of the observation group were dealt with LLLT at the same time.The irradiation energy density was 80 mW/cm^(2),and the irradiation time 30 s.The irradiation was given once a day for 1 week.Visual analogue score(VAS)was used to evaluate the degree of periodontal pain before correction(T0)and 1 d,4 d and 7 d after correction(T1).The plaque index(PLI)and bleeding on probing(BOP)at T0 and T1 were compared between the two groups.The changes of white blood cells and neutrophils in gingival crevicular fluid were analyzed.The levels of inflammatory factors including tumor necrosis factor(TNF)-αand interleukin(IL)-1βin gingival crevicular fluid were detected.Results At T0,there was no significant difference in VAS between the control group and observation group(P>0.05)while the VAS of the observation group being significantly lower than that of the control group at 1 d,4 d and 7 d(P<0.05).Compared with those at T0,the gingival BOP and PLI,number of white blood cells and neutrophils in gingival crevicular fluid and levels of TNF-αand IL-1βin both groups grew significantly at T1 while the root length decreasing dramatically(P<0.05).The gingival BOP and PLI,number of white blood cells and neutrophils in gingival crevicular fluid and levels of TNF-αand IL-1βin the observation group were significantly lower than those in the control group at T1,and the root length was much longer than that in the control group(P<0.05).Conclusions Low intensity laser intervention during orthodontic invisible correction is worthy of clinical promotion as it

关 键 词：弱激光 正畸 隐形矫正 牙周炎症 牙根吸收 

分 类 号：R454.2[医药卫生—治疗学] R783.5[医药卫生—临床医学]