低温等离子髓核成形术联合盘内臭氧注射治疗神经根型颈椎病的临床对照研究  

Low-temperature plasma nucleoplasty combined with intra-disc ozone injection for the treatment of cervical spondylotic radiculopathy:a clinical control study

作　　者：项廷淼[1] 殷世武[1] 卞路 王溢文 XIANG Tingmiao;YIN Shiwu;BIAN Lu;WANG Yiwen(Department of Vascular Intervention and Pain,Hefei Municipal Second People's Hospital(Affiliated Hefei Hospital of Anhui Medical University),Hefei,Anhui Province 230011,China)

机构地区：[1]合肥市第二人民医院(安徽医科大学附属合肥医院)介入血管疼痛科,安徽合肥230011

出　　处：《介入放射学杂志》2023年第4期385-388,共4页Journal of Interventional Radiology

基　　金：合卫科教(2019)172号。

摘　　要：目的 探讨低温等离子髓核成形术联合盘内臭氧注射治疗神经根型颈椎病的临床疗效。方法 选择2018年5月至2021年9月合肥市第二人民医院介入血管疼痛科治疗的神经根型颈椎病患者25例,其中行单纯低温等离子髓核成形术11例(A组),行等离子联合盘内臭氧注射治疗14例(B组)。记录两组术前、术后1周和1、3、6个月的疼痛视觉模拟(VAS)评分和田中靖久颈椎病症状量表评分;术后6个月依据Macnab标准评价临床疗效;记录不良反应发生情况。结果 A组患者术前VAS评分为(6.36±0.92)分,B组患者术前VAS评分为(6.57±0.85)分,差异无统计学意义(P>0.05)。治疗后,两组患者VAS评分均较术前显著降低(P<0.01)。B组术后1周和1、3、6个月的VAS评分分别为(2.43±0.51)、(1.71±0.61)、(1.36±0.49)、(1.29±0.47),均低于A组的(2.91±0.54)、(2.45±0.52)、(2.09±0.3)、(1.82±0.6)分(均P<0.05)。术前,A组患者症状评分(8.91±0.94)分,B组(8.57±1.22)分,差异无统计学意义(P>0.05)。治疗后,两组患者症状评分均较术前显著降低(P<0.01)。B组术后1周和1、3、6个月的症状评分分别为(14.07±1.07)、(14.93±0.73)、(15.5±1.09)、(15.93±0.61)分,均高于A组的(13.18±0.75)、(14.09±0.94)、(14.54±1.08)、(15.36±0.67)分,差异均有统计学意义(均P<0.05)。末次随访时B组整体优良率为92.9%,A组为81.8%。两组均未发生术后并发症。结论 低温等离子髓核成形术联合盘内臭氧注射治疗神经根型颈椎病疗效更佳,且简便安全。Objective To explore the clinical efficacy of low-temperature plasma nucleoplasty combined with intra-disc ozone injection in the treatment of cervical spondylotic radiculopathy(CSR). Methods A total of 25 patients with CSR, who were admitted to the Department of Intervention and Pain of Hefei Municipal Second People's Hospital of China between May 2018 and September 2021 to receive the treatment, were enrolled in this study. The patients were treated with pure low-temperature plasma nucleoplasty(n=11, group A)or with low-temperature plasma nucleoplasty combined with intra-disc ozone injection(n=14, group B). The preoperative and postoperative one-week, as well as 1-, 3-and 6-month pain visual analog scale(VAS) score and Tanaka Yasuji's cervical spondylopathy symptom scale score in both groups were recorded. Six months after treatment, the clinical efficacy was evaluated based on Macnab criteria, and the adverse reactions were documented. Results The preoperative VAS score in group A was(6.36±0.92) points, which was(6.57± 0.85)points in group B, the difference between the two groups was not statistically significant(P<0.05). After treatment,the VAS scores of both groups decreased significantly when compared with preoperative values(P<0.01). The postoperative one-week, as well as 1-, 3-and 6-month VAS scores in group B were(2.43±0.51) points,(1.71±0.61)points,(1.36±0.49) points and(1.29±0.47) points respectively, which were lower than(2.91±0.54) points,(2.45±0.52) points,(2.09±0.3) points and(1.82±0.6) points respectively in group A(all P<0.05). The preoperative symptom scale scores in group A and group B were(8.91±0.94) points and(8.57±1.22) points retrospectively,the difference between the two groups was not statistically significant(P>0.05). In both groups, the postoperative symptom scale scores were significantly lower than the preoperative ones(P<0.01). The postoperative one-week,as well as 1-, 3-and 6-month symptom scale scores in group B were(14.07±1.07) points,(14.93±0.73) points,(15.5±1.09)

关 键 词：低温等离子 髓核成形术 臭氧 神经根型颈椎病 

分 类 号：R687.3[医药卫生—骨科学]