儿童克罗恩病的治疗监测与预后评估  

Treatment monitoring and prognosis assessment of Crohn's disease in children

作　　者：苏雯[1] 肖园[1] SU Wen;XIAO Yuan(Department of Pediatrics,Ruijin Hospital,Shanghai Jiao Tong Medical University,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院儿内科,上海200025

出　　处：《中国实用儿科杂志》2023年第4期266-270,共5页Chinese Journal of Practical Pediatrics

摘　　要：儿童克罗恩病(CD)的治疗目标为临床缓解和黏膜愈合。定期监测疾病活动度评分、炎性标记物水平、影像学及内镜下表现、生长发育及营养状况、生物制剂药物浓度及抗药抗体水平、结核病发生情况有助于评估患儿的治疗反应,指导调整治疗策略。多项指标联合应用的评估效果优于单一指标,优先选择创伤小、放射辐射少的项目。Clinical remission and mucosal healing are treatment target for children with Crohn's disease(CD).Disease activity score,inflammatory marker,magnetic resonance,endoscopic presentation,nutrition and growth,therapeutic drug monitoring as well as screening for TB infection are good markers for evaluating therapeutic response and adjusting treatment strategy.The evaluation effect of the combined application of multiple indicators is better than that of a single indicator.The monitoring method with less trauma and radiation exposure should be considered first.

关 键 词：克罗恩病 儿童 监测 评估 

分 类 号：R72[医药卫生—儿科]