犬丙泊酚全凭静脉麻醉效果  

Effect of Propofol Total Intravenous Anesthesia on Dogs

作　　者：徐浩杰 田锋 郭然 张欣珂[1] XU Hao-jie;TIAN Feng;GUO Ran;ZHANG Xin-ke(College of Veterinary Medicine,Northwest A&F University,Yangling 712100,China;Yanta Brigade of Xi'an Agricultural Comprehensive Law Enforcement Detachment,Xi'an 710000,China;RuiPeng ShengBeiYue Animal Hospital,Nanjing 210000,China)

机构地区：[1]西北农林科技大学动物医学院,陕西杨凌712100 [2]西安市农业综合执法支队雁塔大队,陕西西安710000 [3]瑞鹏贝圣悦宠物医院,江苏南京210000

出　　处：《中国兽医杂志》2023年第5期120-124,共5页Chinese Journal of Veterinary Medicine

摘　　要：为评估丙泊酚全凭静脉麻醉在犬临床手术中的镇痛和镇静效果,本试验选取6只成年犬,按照4个不同剂量[28、32、36、40 mg/(kg·bw·h)]进行丙泊酚全凭静脉麻醉。在麻醉维持期间的各时间点进行80 V电流串刺激,模拟手术疼痛刺激,并于电刺激时监测犬的各项基本生理指标和生物反射分数,同时记录犬的苏醒时间和状况。结果显示,与28、32和40 mg/(kg·bw·h)剂量组相比,36 mg/(kg·bw·h)剂量组可以维持较好的麻醉和镇痛效果,并且苏醒时间较短,苏醒过程平稳,未出现不良反应。以36 mg/(kg·bw·h)的维持剂量对2只实验犬进行绝育术和去势术,均取得了比较理想且安全的麻醉效果。结果表明,犬使用36 mg/(kg·bw·h)剂量的丙泊酚进行全凭静脉麻醉,能够取得满意的麻醉效果,可用于犬短时间手术麻醉。In order to evaluate the analgesic and sedative effects of propofol total intravenous anesthesia on dogs in clinical operation,six adult dogs were selected as experimental animals and received propofol total intravenous anesthesia at four different doses[28,32,36 and 40 mg/(kg·bw·h)].At each time point during the maintenance of anesthesia,the dogs were stimulated with 80 V current series to imitate the pain of surgery,and the basic physiological indicators and biological reflex scores were monitored and recorded during the stimulation.The results showed that the 36 mg/(kg·bw·h)dose group maintained better anesthesia and analgesic effect than the 28,32 and 40 mg/(kg·bw·h)dose groups,had short awake time and stable process,and caused no adverse reactions;two experimental dogs were sterilized and castrated at a maintenance dose of 36 mg/(kg·bw·h),with satisfactory and safe anesthesia outcomes.Thus,propofol total intravenous anesthesia at 36 mg/(kg·bw·h)gives satisfactory anesthesia outcome,and can be used for short-term surgical anesthesia in dogs.

关 键 词：犬 丙泊酚 全凭静脉麻醉 麻醉效果 

分 类 号：S857.124[农业科学—临床兽医学]