Kobayashi前体在有机合成中的研究进展  

Research Progress on Kobayashi Precursors in Organic Synthesis

作　　者：张学清 巴哈尔古丽·别克吐尔逊 张俊 ZHANG Xue-qing;Bahaerguli·Bieketuerxun;ZHANG Jun(University and College Key Lab of Natural Product Chemistry and Application in Xinjiang,School of Chemistry and Environmental Science,Yili Normal University,Xinjiang Yining 835000,China)

机构地区：[1]伊犁师范大学化学与环境科学学院,新疆普通高等学校天然产物化学与应用重点实验室,新疆伊宁835000

出　　处：《广州化工》2023年第5期25-29,共5页GuangZhou Chemical Industry

基　　金：伊犁师范大学校级一般基金项目(No:2021YSYB081)。

摘　　要：苯炔作为一种高活性的有机合成中间体,在有机合成中有着非常重要的作用。特别是以邻三甲基硅基苯基三氟甲磺酸酯为苯炔前体的研究受到了化学工作者的广泛关注。邻三甲基硅基苯基三氟甲磺酸酯在一定条件下可以与多种的有机物发生反应,按其反应的机理可以分为四类:(1)亲核加成或多组分反应;(2)σ-键的插入反应;(3)环化加成反应;(4)过渡金属参与催化的反应。Benzyne,as a highly active organic synthesis intermediate,plays a very important role in organic synthesis.In particular,the study of o-trimethylsilyl phenyl trifluoromethanesulfonate as benzyne precursor has received extensive attention from chemists.O-trimethylsilyl phenyl trifluoromethanesulfonate was react with a variety of organic substances under certain conditions,and was divided into four categories according to the reaction mechanism:nucleophilic addition or multi-component reaction,σ-bond insertion reaction,cycloaddition reaction,and transition metal catalyzed reaction.

关 键 词：苯炔 邻三甲基硅基苯基三氟甲磺酸酯 

分 类 号：O621.3[理学—有机化学]