不明原因不孕症患者HSG术后IUI治疗效果分析  

Analysis of IUI treatment effect in patients with unexplained infertility after HSG

作　　者：严永旭 赵夏丽 姜根风 陈思文 洪程程 胡卫华 YAN Yongxu;ZHAO Xiali;JIANG Genfeng;CHEN Siwen;HONG Chengcheng;HU Weihua(Department of Reproductive Medicine,The First Affiliated Hospital of Wannan Medical College,Wuhu 241001,China)

机构地区：[1]皖南医学院第一附属医院弋矶山医院生殖医学科,安徽芜湖241001

出　　处：《皖南医学院学报》2023年第2期134-136,共3页Journal of Wannan Medical College

基　　金：安徽高校研究生科学研究项目(YJS20210550)。

摘　　要：目的:探讨子宫输卵管造影(HSG)术后不同时间对不明原因不孕症(UI)患者行宫腔内人工授精(IUI)助孕的妊娠结局影响。方法:回顾性分析弋矶山医院生殖医学科2016年1月~2021年6月UI患者行IUI共333周期,根据其行HSG与IUI的间隔时间分为2组,A组为HSG术后3个月内行IUI助孕,共157个周期,B组为HSG术后3个月以上行IUI助孕,共176个周期,分析其术后妊娠情况。结果:A组单周期妊娠率及活产率分别低于B组(14.01%vs. 22.73%,11.46%vs. 19.89%)(P<0.05),但两组间流产率(18.18%vs. 12.50%)差异无统计学意义(P>0.05)。结论:UI患者HSG术后何时行IUI均不增高其流产率,HSG术后过早行IUI助孕并不能提高UI患者单周期妊娠率及活产率。Objective:To investigate the effect of different time after hysterosalpingography(HSG)on the pregnancy outcome of intrauterine artificial insemination(IUI)in patients with unexplained infertility(UI).Methods:Retrospective analysis was performed in the UI patients following 333 cycles of IUI in our department between January 2016 and June 2021.According to the interval between HSG and IUI,UI patients were divided into group A and group B.patients in group A received IUI within 3 months after HSG(a total of 157 cycles),and those in group B underwent IUI more than 3 months after HSG(a total of 176 cycles).The postoperative pregnancy was analyzed.Results:The single cycle pregnancy rate(14.01%)and live birth rate(11.46%)of UI patients with IUI within 3 months after HSG were significantly lower than those of UI patients with IUI more than 3 months after HSG(22.73%and 19.89%)(P<0.05),yet there was no significant difference in abortion rate(18.18%and 12.50%)between the two groups(P>0.05).Conclusion:The timing of IUI performed in UI patients after HSG will not increase the abortion rate,and too early assisted pregnancy by IUI after HSG will not improve the single cycle pregnancy rate and live birth rate of UI patients,either.

关 键 词：不明原因不孕症 子宫输卵管造影 宫腔内人工授精 妊娠率 

分 类 号：R711.6[医药卫生—妇产科学] R714.8[医药卫生—临床医学]