多波长红外尿糖检测技术研究  

Research on Multi-Wavelength Infrared Urine Glucose Detection Technology

作　　者：梅竹松 严荣国[1] 徐涛[2] 魏梦林 MEI Zhusong;YAN Rongguo;XU Tao;WEI Menglin(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Department of Neurosurgery,Shanghai Changzheng Hospital,Shanghai 200003,China)

机构地区：[1]上海理工大学健康科学与工程学院,上海200093 [2]上海长征医院神经外科,上海200003

出　　处：《计算机测量与控制》2023年第5期101-107,113,共8页Computer Measurement &Control

摘　　要：糖尿病一直以来是人们关注的重点,尿糖是衡量糖尿病的关键指标,针对糖尿病的快速精准检测的迫切需求,研究多波长红外尿糖检测技术,推动近红外光谱技术应用于尿糖浓度的检测以及糖尿病的预防与诊断;选取吸收光谱特性与葡萄糖浓度变化相关性较好的近红外光源(940 nm、1150 nm、1310 nm、1550 nm),进行硬件选型、光学结构系统、信号探测电路以及软件设计,并进行光谱信息预处理以及浓度模型研究,最终配合上位机实现尿糖浓度的处理、存储和实时检测等功能;通过实验测试环节,检测得到了尿糖浓度值,并经过计算R^(2)=0.9928,误差不大于4.2%,验证了此检测技术具有出色的相关性、准确性;该技术研究最终证实了多波长红外尿糖检测的可行性以及稳定性,相比传统检测方法有较好的创新性,同时可以满足糖尿病快速准确检测的需求,保障了人们的健康安全,有利于推动近红外光谱应用于临床尿糖检测的进程。Diabetes has always been the focus of attention,urine glucose is a key indicator to measure diabetes,in view of the urgent need for rapid and accurate detection of diabetes,a multi-wavelength infrared urine glucose detection technology was researched,and a near-infrared spectroscopy technology application was promoted to be used in the detection of urine glucose concentration and the prevention and diagnosis of diabetes.The near-infrared light sources(940 nm,1150 nm,1310 nm,1550 nm)with the good correlation between absorption spectrum characteristics and glucose concentration changes were selected,which completed the hardware selection,optical structure system,signal detection circuit and software design,the research for the spectral information preprocessing and concentration model was carried out,and finally the functions of urine glucose concentration processing,storage and real-time detection were realized with the host computer.Through experimental testing and inspection,the urine glucose concentration value was obtained,and the determination coefficient R^(2) of the model was 0.9928 after the calculation,with an error of no more than 4.2%,which verified that the detection technology had the excellent correlation and accuracy.This technical research finally confirms the feasibility and stability of the multi-wavelength infrared urine glucose detection,which is better innovative than traditional detection methods,and it can meet the needs of rapid and accurate detection of diabetes,ensure people s health and safety,and is profit to promote the application of near-infrared spectroscopy to clinical urine glucose detection.

关 键 词：近红外光谱 尿糖浓度 朗伯比尔定律 遗传算法 偏最小二乘法 

分 类 号：TN215[电子电信—物理电子学]