肺部超声评分与新生儿呼吸窘迫患儿氧合能力的相关性  

Correlation between pulmonary ultrasound score and oxygen-carrying capacity in neonatal respiratory distress syndrome

作　　者：胡令英[1] 张俊霞 HU Ling-ying;ZHANG Jun-xia(Department of Pediatrics,Binzhou Central Hospital,Binzhou 251700,China)

机构地区：[1]滨州市中心医院儿科一病区,山东滨州251700

出　　处：《中国处方药》2023年第5期131-134,共4页Journal of China Prescription Drug

摘　　要：目的 研究肺部超声评分与新生儿呼吸窘迫患儿氧合能力的相关性。方法 选取某院2018年4月~2021年4月收治的67例新生儿呼吸窘迫综合征患儿作为研究对象,根据患者7 d预后分为预后良好组(n=57)和预后不良组(n=10),对比两组患儿一般资料[性别、胎龄、分娩方式、肺部超声评分、氧合指数(PaO_(2)/FiO_(2))、新生儿窒息评分、新生儿危重病例评分],分析肺部超声评分与PaO_(2)/FiO_(2)、新生儿窒息评分和新生儿危重病例评分的相关性,绘制乘积极限(Kaplan-Meier,KM)曲线,分析肺部超声评分对新生儿呼吸窘迫患儿预后的评估价值。结果 两组患儿性别、胎龄和分娩方式比较,差异无统计学意义(P>0.05);与预后良好组患儿相比,预后不良组患儿肺部超声评分显著更高,PaO_(2)/FiO_(2)、新生儿窒息评分和新生儿危重病例评分显著更低,差异具有统计学意义(P<0.05);相关性分析发现,呼吸窘迫综合征患儿肺部超声评分与PaO_(2)/FiO_(2)、新生儿窒息评分以及新生儿危重病例评分呈负相关性(P<0.05);67例患儿中14 d转归良好58例,转归不良9例。据肺部超声评分均值进行分层,并绘制KM曲线,30 d后转归良好率分别为98.14%和38.46%,差异具有统计学意义(P<0.05)。结论 肺部超声评分与新生儿呼吸窘迫患儿氧合能力的水平存在明显负相关性,且肺部超声评分与预后存在一定关系。Objective To study the correlation between pulmonary ultrasound score and oxygen-ation capacity in neonatal respiratory distress syndrome.Methods Sixty-seven neonates with neonatal respiratory distress syndrome in our hospital from April 2018 to April 2021 were enrolled.Classified into good prognosis group(n=57)and poor prognosis group(n=10)according to the 7-day prognosis.General information including gender,gestational age,mode of delivery,lung ultrasound score,oxygenation index(PaO_(2)/FiO_(2)),neonatal asphyxia score,neonatal critical case score were compared between two groups.The correlation of pulmonary ultrasound score with PaO_(2)/FiO_(2),neonatal asphyxia score,and neonatal critical illness scores was discussed.Kaplan-Meier(KM)curve was drawn to analyze the prognostic survival status,then the value of pulmonary ultrasound score in evaluating the prognosis of neonates with neonatal respiratory distress syndrome was verified.Results The gender,gestational age and delivery mode yielded no statistical difference between two groups(P>0.05).Compared with good prognosis group,poor prognosis group had higher pulmonary ultrasound scores,and lower PaO_(2)/FiO_(2),neonatal asphyxia and neonatal critical illness scores,with statistical significance(P<0.05).Correlation analysis showed that pulmonary ultrasound scores of neonates with neonatal respiratory distress syndrome were negatively correlated with PaO_(2)/FiO_(2),neonatal asphyxia and neonatal critical illness scores,with statistical significance(P<0.05).Among the 67 childrens,58 had good outcomes and 9 had poor outcomes at 14 days.The mean value of pulmonary ultrasound scores was stratified and the KM curve was drawn.The good recovery rates after 30 days were 98.14%and 38.46%,respectively,with statistical difference(P<0.05).Conclusion The pulmonary ultrasound score is negatively correlated with the oxygen-ation capacity in neonates with neonatal respiratory distress syndrome,and also has a certain correlation with the prognosis of neonates.

关 键 词：肺部超声 新生儿呼吸窘迫综合征 氧合能力 预后 

分 类 号：R722.1[医药卫生—儿科] R445.1[医药卫生—临床医学]