敛疮解毒方中药含漱护理方案在预防放射性口腔黏膜炎中的效果研究  

Study on the effect of gargling nursing plan of Lianchuang Jiedu prescription in the prevention of radiation oral mucositis

作　　者：徐莹[1] 李黎[1] 黄萍 XU Ying;LI Li;HUANG Ping(Tumor Radiotherapy Department,the First People's Hospital of Changzhou,Changzhou 213000,China)

机构地区：[1]常州市第一人民医院肿瘤放射治疗科,江苏常州213000

出　　处：《医药高职教育与现代护理》2023年第3期244-248,共5页Medical Higher Vocational Education and Modern Nursing

基　　金：常州市第一人民医院护理专项预研基金资助项目(编号:yy2020011)。

摘　　要：目的观察敛疮解毒方中药含漱护理方案在预防放射性口腔黏膜炎中的临床应用效果。方法选取常州市第一人民医院2020年2月至2022年2月收入院初次接受同步放化疗鼻咽癌放疗患者110例作为研究对象,将其随机分为对照组55例,观察组55例。观察组采用鼻咽癌放疗常规护理+敛疮解毒方中药含漱,对照组采用鼻咽癌放疗常规护理+2.5%碳酸氢钠含漱,观察两组患者放射性口腔黏膜炎的发生情况。结果观察组患者初次发生Ⅰ级口腔黏膜炎的时间为(28.05±16.20)d,晚于对照组的(16.15±10.84)d(t=4.531,P<0.001);观察组患者初次发生Ⅱ级口腔黏膜炎的时间为(38.53±10.09)d,晚于对照组的(30.16±14.44)d(t=3.521,P=0.001)。在放疗第21天,观察组与对照组Ⅱ级及以上口腔黏膜炎发生率分别为9.09%vs.27.27%(χ^(2)=6.111,P=0.024),观察组患者口腔黏膜炎分级情况较对照组发生程度轻(Z=-2.642,P=0.011);第28天口腔黏膜炎的发生率分别为12.73%vs.41.82%(χ^(2)=11.733,P=0.001),观察组患者口腔黏膜炎分级情况较对照组发生程度轻(Z=-2.180,P=0.040);第35天口腔黏膜炎的发生率分别为27.27%vs.65.45%(χ^(2)=16.122,P<0.001),观察组患者口腔黏膜炎分级情况较对照组轻(Z=-2.398,P=0.025)。结论护理人员主导参与的敛疮解毒方中药含漱方案能延迟放疗患者Ⅰ级、Ⅱ级口腔黏膜炎的发生时间,降低Ⅱ级及以上口腔黏膜炎发生率,减轻口腔黏膜炎的严重程度。Objective To observe the clinical application effect of gargle nursing plan of Lianchuang Jiedu prescription in the prevention of radiation oral mucositis.Methods A total of 110 patients who were in the First People's Hospital of Changzhou from Februory 2020 to February 2022,with radiotherapy for nasopharyngeal carcinoma were randomly divided into 55 cases in the control group and 55 cases in the observation group.To observe the occurrence of radiation oral mucositis,the observation group used nasopharyngeal cancer radiotherapy routine nursing+Rinse with traditional Chinese medicine,and the control group used nasopharyngeal cancer radiotherapy nursing routine+2.5%sodium bicarbonate containing gargling.Results The time of first occurrence of gradeⅠoral mucositis of patients in the observation group(28.05±16.20)days was later than that of ones in the control group(16.15±10.84)days(t=4.531,P<0.001);the time for the first occurrence of gradeⅡoral mucositis of patients in the observation group(38.53±10.09)days was later than that of ones in the control group(30.16±14.44)days(t=3.521,P=0.001).On the 21st day of radiotherapy,the incidence of gradeⅡand above oral mucositis of patients in the observation group and the control group was 9.09%vs.27.27%,respectively(χ^(2)=6.111,P=0.024),the grade of oral mucositis of patients in the observation group was less severe than that of ones in the control group(Z=-2.642,P=0.011);the incidence of patients on the 28th day was 12.73%vs.41.82%,respectively(χ^(2)=11.733,P=0.001),the grade of oral mucositis of patients in the observation group was less severe than that of ones in the control group(Z=-2.180,P=0.040);The incidence of patients on the 35th day was 27.27%vs.65.45%(χ^(2)=16.122,P<0.001).The grade of oral mucositis of patients in the observation group was less severe than that of ones in the control group(Z=-2.398,P=0.025).Conclusions The traditional Chinese medicine gargling program led by nursing staff could delay the occurrence of gradeⅠand gradeⅡoral mucosi

关 键 词：中药含漱 鼻咽癌 放射性口腔黏膜炎 放射治疗 护理方案 

分 类 号：R473.73[医药卫生—护理学]