头皮神经阻滞联合右美托咪定用于帕金森患者脑深部电刺激手术的效果  

Effectiveness of Scalp Nerve Block Combined with Dexmedetomidine for Deep Brain Electrical Stimulation Surgery in Parkinson's Patients

作　　者：蓝建宁 LAN Jianning(Department of Anesthesiology,Union Hospital of Fujian Medical University,Fuzhou,Fujian Province,350001 China)

机构地区：[1]福建医科大学附属协和医院麻醉科,福建福州350001

出　　处：《中外医疗》2023年第5期59-62,共4页China & Foreign Medical Treatment

摘　　要：目的 分析头皮神经阻滞联合右美托咪定用于帕金森患者脑深部电刺激手术的效果。方法 方便选取2019年1月—2020年12月福建医科大学附属协和医院收治的66例帕金森患者为研究对象,根据随机数表法分为两组,对照组33例予以切口局部浸润麻醉联合右美托咪定,研究组33例予以头皮神经阻滞联合右美托咪定。对比两组的血流动力学指标及脑电双频指数。结果 手术开始时(T1)、一侧钻孔时(T2)、对侧钻孔时(T3)及术毕时(T4),两组患者的心率(HR)、平均动脉压(MAP)水平及呼吸频率均低于入室时(T0),且研究组低于对照组,差异有统计学意义(P<0.05),而各时间点两组的血氧饱和度(SpO_(2))与T0时比较,且两组间比较,差异无统计学意义(P>0.05)。研究组脑电双频指数在停时使用麻醉药时[(78.78±6.33) vs (63.63±4.25)]、神经学测试时[(90.86±5.27) vs (82.67±4.31)]均高于对照组,差异有统计学意义(t=11.415、6.911,P<0.001)。结论 头皮神经阻滞联合右美托咪定用于帕金森患者脑深部电刺激手术的效果显著,有助于稳定血流动力学指标,并获得良好镇静水平。Objective To analyze the effect of scalp nerve block combined with dexmedetomidine for deep brain electrical stimulation surgery in Parkinson's patients.Methods 66 Parkinson's patients admitted to the Affiliated Union Hospital of Fujian Medical University from January 2019 to December 2020 were conveniently selected as the study subjects.They were divided into two groups using a random number table method.The control group received local infiltration anesthesia combined with dexmedetomidine,while the study group received scalp nerve block combined with dexmedetomidine.Compared the hemodynamic indicators and bispectral index of EEG between the two groups.Results The heart rate(HR),mean arterial pressure(MAP)and respiratory rate of the patients in the two groups at the beginning of surgery(T1),at the time of drilling on one side(T2),at the time of drilling on the other side(T3)and at the end of surgery(T4)were lower than those at the time of entering the room(T0),and the study group was lower than the control group,the difference was statistically significant(P<0.05).At each time point,the oxygen saturation(SpO2)of the two groups was compared with that at T0,and compared between the two groups,the difference was not statistically significant(P>0.05).The bispectral index of EEG in the study group was significantly higher than that in the control group when anesthetics were stopped[(78.78±6.33)vs(63.63±4.25)],and when neurology tests were conducted[(90.86±5.27)vs(82.67±4.31)],the difference was statistically significant(t=11.415,6.911,P<0.001).Conclusion Scalp nerve block combined with dexmedetomidine for deep brain electrical stimulation in Parkinson´s patients is effective and helps stabilize hemodynamic indices and obtained good sedation level.

关 键 词：头皮神经阻滞 右美托咪定 帕金森 脑深部电刺激手术 血流动力学指标 脑电双频指数 

分 类 号：R4[医药卫生—临床医学]