七氟醚吸入麻醉和艾司氯胺酮静脉麻醉用于手术患者的临床价值  

Clinical Value of Sevoflurane Inhalation Anesthesia and Esketamine Intravenous Anesthesia for Surgical Patients

作　　者：方锐伦 郑耀明 黄连芳 FANG Ruilun;ZHENG Yaoming;HUANG Lianfang(Department of Anesthesiology,Jiangmen People's Hospital,Jiangmen,Guangdong Province,529000 China)

机构地区：[1]江门市人民医院麻醉科,广东江门529000

出　　处：《中外医疗》2023年第5期116-119,共4页China & Foreign Medical Treatment

摘　　要：目的 分析七氟醚吸入麻醉和艾司氯胺酮静脉麻醉方法用于手术中对患者麻醉的临床价值。方法 方便选取2020年8月—2021年8月期间江门市人民医院收治的行手术治疗的患者56例为研究对象,用随机数字法分为A组和B组,各28例。A组采用七氟吸入麻醉,B组采用艾司氯胺酮静脉麻醉。对比两组间的麻醉效果。结果 B组中患者睁眼时间为(16.34±3.15)min,拔管时间为(10.58±1.87)min,优于A组的(27.45±6.05)、(15.29±2.05)min,差异有统计学意义(t=8.619、8.982,P<0.001)。两组不良反应发生率比较,差异无统计学意义(χ^(2)=0.269,P>0.05)。B组患者在术后即刻、术后1 d、术后3 d的认知功能评分为(26.98±0.32)分、(27.85±0.51)分、(28.33±0.55)分,均优于A组(26.38±0.47)分、(27.11±0.30)分、(27.54±0.48)分,差异有统计学意义(t=5.584、6.618、5.726,P<0.001),术后7 d两组患者的术后认知水平比较,差异无统计学意义(P>0.05)。结论 外科手术患者在麻醉时使用艾司氯胺酮静脉麻醉与七氟醚吸入麻醉的安全性相同,但艾司氯胺酮静脉麻醉能加速患者的麻醉恢复时间与意识清醒速率。Objective To analyze the clinical value of sevoflurane inhalation anesthesia and esketamine intravenous anesthesia methods used for anesthesia of patients in surgery.Methods 56 patients who underwent surgery treatment admitted to Jiangmen People's Hospital from August 2020 to August 2021 were conveniently selected as the research subjects.They were randomly divided into group A and group B,with 28 patients in each group.Group A was anesthetized with sevoflurane inhalation,while group B was anesthetized with intravenous infusion of Esketamine.Compared the anesthesia effects between the two groups.Results The opening time of patients in group B was(16.34±3.15)min,and the extubation time was(10.58±1.87)min,which was superior to group A's(27.45±6.05)min and(15.29±2.05)min,and the difference was statistically significant(t=8.619,8.982,P<0.001).There was no statistically significant difference in the incidence of adverse reactions between the two groups(χ^(2)=0.269,P>0.05).The cognitive function scores of Group B patients were(26.98±0.32)points,(27.85±0.51)points,and(28.33±0.55)points immediately after surgery,1 day after surgery,and 3 days after surgery,all of which were better than those of group A(26.38±0.47)points,(27.11±0.30)points,and(27.54±0.48)points,the differences was statistically significant(t=5.584,6.618,5.726,P<0.001).There was no statistically significant difference in postoperative cognitive level between the two groups 7 days after surgery(P>0.05).Conclusion The safety of using Esketamine intravenous anesthesia and sevoflurane inhalation anesthesia for surgical patients during anesthesia is the same,but esketamine intravenous anesthesia can accelerate the recovery time of anesthesia and the rate of consciousness in patients.

关 键 词：七氟醚吸入麻醉 艾司氯胺酮 静脉麻醉 临床价值 外科手术 

分 类 号：R5[医药卫生—内科学]