酒石酸布托啡诺复合丙泊酚应用于无痛胃肠镜检查中的效果研究  

Effect of Butorphanol Tartrate Combined with Propofol in Painless Gastroenteroscopy

作　　者：王月民 李灵君 桑慧 WANG Yuemin;LI Lingjun;SANG Hui(Department of Anesthesiology,Heze Sixth People's Hospital,Heze,Shandong Province,274000 China;Department of Inpatient Pharmacy,Heze Sixth People's Hospital,Heze,Shandong Province,274000 China)

机构地区：[1]菏泽市第六人民医院麻醉科,山东菏泽274000 [2]菏泽市第六人民医院住院药房,山东菏泽274000

出　　处：《中外医疗》2023年第7期15-18,33,共5页China & Foreign Medical Treatment

摘　　要：目的 探讨酒石酸布托啡诺复合丙泊酚应用于无痛胃肠镜检查中的效果。方法 方便选取2021年1—12月在菏泽市第六人民医院接受无痛胃肠镜检查的患者108例为研究对象,按照随机数表法分为两组,每组54例。研究组应用酒石酸布托啡诺联合丙泊酚麻醉,对照组应用芬太尼联合丙泊酚麻醉。针对两组麻醉效果、麻醉起效时间、丙泊酚使用量、苏醒时间,麻醉前、睫毛反射消失时与苏醒时的心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO_(2))指标,以及麻醉不良反应发生率进行对比。结果 研究组麻醉的优良率为96.30%与对照组的87.04%比较,差异无统计学意义(χ^(2)=1.939,P>0.05)。研究组麻醉起效时间、丙泊酚使用量、苏醒时间均优于对照组,差异有统计学意义(P<0.001)。睫毛反射消失时,研究组各项生命体征指标较对照组更平稳,即HR、MAP、SpO_(2)指标较对照组高,差异有统计学意义(P<0.001)。研究组不良反应发生率为3.70%较对照组的16.67%低,差异有统计学意义(χ^(2)=4.960,P<0.05)。结论 无痛胃肠镜检查中应用酒石酸布托啡诺复合丙泊酚麻醉具有起效快速、患者苏醒迅速等特点,能够有效维持生命体征的稳定性,安全可靠。Objective To investigate the effect of butorphanol tartrate combined with propofol in painless gastroenteroscopy.Methods A total of 108 patients who received painless gastroenteroscopy in Heze Sixth People's Hospital from January to December 2021 were conveniently selected as the study objects and divided into two groups according to random number table method,with 54 patients in each group.The study group was anesthetized with butorphanol tartrate combined with propofol,while the control group was anesthetized with fentanyl combined with propofol.Anesthesia effect,onset time of anesthesia,dosage of propofol,time to recovery,heart rate(HR),mean arterial pressure(MAP),blood oxygen saturation(SpO_(2))before anesthesia,when eyelash reflex disappeared,and when recovery,and the incidence of adverse reactions to anesthesia were compared between the two groups.Results The excellent and good rate of anesthesia in the research group was 96.30%compared to 87.04%in the control group,the difference was not statistically significant(χ^(2)=1.939,P>0.05).The onset time of anesthesia,the amount of propofol and the recovery time of the study group were superior than those of the control group,and the difference was statistically significant(P<0.001).When eyelash reflex disappeared,the vital signs of the research group were more stable than that of the control group,that was,HR,MAP,SpO_(2) indexes were higher than that of the control group,the difference was statistically significant(P<0.001).incidence of adverse reactions(3.70%)in the study group was lower than in the control group(16.67%),the difference was statistically significant(χ^(2)=4.960,P<0.05).Conclusion The application of butorphanol tartrate combined with propofol anesthesia in painless gastroscopy has the characteristics of rapid onset and rapid recovery of patients,which can effectively maintain the stability of vital signs and is safe and reliable.

关 键 词：酒石酸布托啡诺 丙泊酚 无痛胃肠镜 

分 类 号：R4[医药卫生—临床医学]