沙漠干燥环境下软组织开放伤的感染特点  

The infection characteristics of soft tissue open wound in the dry desert environment

作　　者：马海鑫 李庆忠[1] 李佳伟 胥志敏 严乃复 MA Hai-xin;LI Qing-zhong;LI Jia-wei;XU Zhi-min;YAN Nai-fu(Dept of Orthopaedics,the 63600 Military Hospital of CPLA,Jiuquan,Gansu 732750,China)

机构地区：[1]中国人民解放军63600部队医院骨科,甘肃酒泉732750 [2]中国人民解放军63600部队医院检验科,甘肃酒泉732750

出　　处：《临床骨科杂志》2023年第3期448-450,共3页Journal of Clinical Orthopaedics

摘　　要：目的研究沙漠干燥环境下软组织开放伤的感染特点。方法将54只成年健康雄性SD大鼠制成背部软组织缺损的开放伤模型,测量伤前及伤后大鼠肛温,观察伤后创面感染情况,取创面分泌物进行细菌培养、鉴定及药敏实验,并对创面组织细菌含量计数。结果大鼠伤后48 h肛温最高,创面结痂干燥、变为暗红色,痂下组织水肿明显、组织变脆,并可见明确感染灶及脓液,组织细菌含量达到5.3~5.8(5.57±0.27)×10^(5) cfu/g。创面细菌培养结果提示细菌对多种抗生素敏感。结论沙漠地区干燥环境使创面感染时间延迟,创面清创时间可适当延迟。Objective To study the infection characteristics of soft tissue open wounds in dry desert environment.Methods Fifty-four adult male SD rats were made into an open wound model of back soft tissue defects.The rectal temperature of the rats before and after the trauma was measured.The wound infection was observed after the trauma.The wound secretion was taken for bacterial culture,identification and drug sensitivity tests,and the bacterial content in the wound tissue was counted.Results The rectal temperature of rats was the highest at 48 h after trauma,the wound scab became dry and dark red,the tissue under the scab became edema and brittle,and the infection focus and pus were clear.The bacterial content in the tissue reached 5.3~5.8(5.57±0.27)×10^(5) cfu/g.The results of wound bacterial culture suggested that bacteria were sensitive to various antibiotics.Conclusions The dry environment in desert areas delays soft tissue trauma infection,and the wound debridement time can be appropriately delayed.

关 键 词：沙漠干燥环境 四肢 软组织外伤 感染 大鼠 

分 类 号：R632[医药卫生—外科学] R641[医药卫生—临床医学]