睡眠质量与T2DM患者发生糖尿病视网膜病变的相关性分析  

Correlation Between Sleep Quality and Diabetic Retinopathy in Patients With T2DM

作　　者：郭海燕[1] 柯欣欣 郑丽钟 GUO Haiyan;KE Xinxin;ZHENG Lizhong(Department of Endocrinology,Quanzhou Hospital of Traditional Chinese Medicine,Quanzhou Fujian 362000,China)

机构地区：[1]泉州市中医院内分泌科,福建泉州362000

出　　处：《中国卫生标准管理》2023年第9期105-108,共4页China Health Standard Management

摘　　要：目的分析睡眠质量与2型糖尿病(type 2 diabetes mellitus,T2DM)患者发生糖尿病视网膜病变的相关性。方法回顾性分析泉州市中医院2020年3月—2022年3月收治的98例T2DM患者的临床资料,根据眼科专科检查结果将其分为病变组(发生糖尿病视网膜病变患者,n=37)和未病变组(未发生视网膜病变患者,n=61)。比较两组性别、年龄、糖尿病病史、空腹血糖、餐后2 h血糖、合并高血压、高血脂等临床资料,分析T2DM患者发生糖尿病视网膜病变的影响因素,再对比两组患者睡眠质量[匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)],采用Spearman相关系数分析睡眠质量与T2DM患者发生糖尿病视网膜病变的相关性。结果病变组糖尿病病史、空腹血糖、餐后2 h血糖、合并高血压、高血脂均高于未病变组(P <0.05)。经非条件Logistic多元逐步回归分析,空腹血糖、餐后2 h血糖不是T2DM患者发生糖尿病视网膜病变的影响因素(P> 0.05),糖尿病病史、合并高血压、高血脂均是T2DM患者发生糖尿病视网膜病变的影响因素(P <0.05)。病变组患者PSQI评分高于未病变组(P<0.05),睡眠质量PSQI评分与T2DM患者发生糖尿病视网膜病变呈正相关(P <0.05)。结论 T2DM患者发生糖尿病视网膜病变的影响因素较多,睡眠质量PSQI评分与其呈正相关,PSQI评分越高,患者越容易发生糖尿病视网膜病变。Objective To analyze the correlation between sleep quality and diabetic retinopathy in patients with type 2 diabetes mellitus(T2DM).Methods The clinical data of 98 patients with T2DM admitted to Quanzhou Hospital of Traditional Chinese Medicine from March 2020 to March 2022 were retrospectively analyzed,and they were divided into lesion group(patients with diabetic retinopathy,n=37)and non-lesion group(patients without retinopathy,n=61)according to the results of specialized ophthalmic examination.Clinical data of gender,age,diabetes mellitus history,fasting blood glucose,2 h postprandial blood glucose,hypertension and hyperlipidemia were compared between the two groups.The influencing factors of diabetic retinopathy in patients with T2DM were analyzed,and the sleep quality[Pittsburgh sleep quality index(PSQI)]was compared between both groups.Spearman correlation coefficient was used to analyze the correlation between sleep quality and diabetic retinopathy in patients with T2DM.Results The history of diabetes mellitus,fasting blood glucose,2 h postprandial blood glucose,hypertension and hyperlipidemia in lesion group were all higher than those in non-lesion group(P<0.05).After unconditioned Logistic multivariate stepwise regression analysis,fasting blood glucose and 2 h postprandial blood glucose were not the influencing factors of diabetic retinopathy in patients with T2DM(P>0.05),and the history of diabetes mellitus,hypertension and hyperlipidemia were influencing factors of the occurrence of diabetic retinopathy in patients with T2DM(P<0.05).PSQI score of patients in lesion group was higher than that in non-lesion group(P<0.05),and the sleep quality PSQI score was positively correlated with diabetic retinopathy in patients with T2DM(P<0.05).Conclusion There are many influencing factors of the occurrence of diabetic retinopathy in patients with T2DM,and PSQI score of sleep quality is positively correlated with the occurrence.The higher the PSQI score is,the more likely the patient is to develop diabetic retinop

关 键 词：睡眠质量 2型糖尿病 糖尿病视网膜病变 相关性分析 血糖 影响因素 

分 类 号：R587[医药卫生—内分泌]