预后营养指数在腹腔镜贲门癌根治术后并发症的预测价值  

Predictive Value of Prognostic Nutritional Index in Postoperative Complications after Laparoscopic Radical Resection of Cardia Cancer

作　　者：梁秋豪 蔺瑞江 袁博文 王晨晗 马敏杰[2] 韩彪[2] LIANG Qiuhao;LIN Ruijiang;YUAN Bowen(The First School of Clinical Medicine,Lanzhou University,Gansu 730000,China)

机构地区：[1]兰州大学第一临床医学院,730000 [2]兰州大学第一医院胸外科,730000

出　　处：《医学研究杂志》2023年第5期106-110,共5页Journal of Medical Research

基　　金：甘肃省自然科学基金资助项目(21JR1RA118);甘肃省自然科学基金青年科学基金资助项目(21JR1RA107)。

摘　　要：目的探究预后营养指数(prognostic nutritional index,PNI)在腹腔镜贲门癌根治术后并发症的预测价值。方法回顾性收集兰州大学第一医院胸外科2016年1月~2022年1月收治的66例行腹腔镜贲门癌根治术的贲门癌患者的临床资料,根据受试者工作特征(receiver operating characteristic,ROC)曲线确定预测术后并发症的最佳截断值,对患者进行分组,分析两组患者之间的基本特征及术后并发症的差异,再根据患者是否发生术后并发症分为无并发症组和有并发症组,通过单因素和多因素分析探讨相关指标对腹腔镜贲门癌根治术后并发症发生的影响。结果高PNI组术后总体并发症发生率、术后感染发生率、切口延迟愈合发生率均低于低PNI组。年龄、PNI、术前白细胞计数、术前淋巴细胞计数、术前单核细胞计数、白蛋白、身高、体重为影响腹腔镜贲门癌根治术后并发症的可能危险因素。PNI、体重为影响术后并发症的独立保护因素。结论PNI在腹腔镜贲门癌根治术后并发症中具有一定的预测价值,PNI为术后并发症的独立影响因素。Objective To investigate the predictive value of prognostic nutritional index(PNI)in postoperative complications after laparoscopic radical resection of cardia cancer.Methods The clinical data of 66 patients with cardiac cancer who underwent laparoscopic radical resection for cardiac cancer who were admitted to the Department of Thoracic Surgery of the First Hospital of Lanzhou University from January 2016 to January 2022 were retrospectively collected and determined according to the receiver operating characteristic(ROC)curve.The best cut-off value for predicting postoperative complications was used to divide the patients into two groups and analyze the differences in basic characteristics and postoperative complications between the two groups,and then the patients were divided into non-complication group and those with complications according to whether postoperative complications occurred.In this group,the influence of related indicators on the occurrence of complications after laparoscopic radical resection of cardia cancer was investigated through univariate and multivariate analysis.Results The overall postoperative complication rate,postoperative infection rate,and incision delayed healing rate in the high PNI group were lower than those in the low PNI group.Age,PNI,preoperative white blood cell count,preoperative lymphocyte count,preoperative monocyte count,albumin,height and weight were the possible risk factors for complications after laparoscopic radical resection of cardia cancer.PNI and body weight were independent protective factors affecting postoperative complications.Conclusion PNI has a certain predictive value in postoperative complications after laparoscopic radical resection of cardia cancer,and PNI is an independent influencing factor of postoperative complications.

关 键 词：预后营养指数 腔镜手术 贲门癌根治术 术后并发症 

分 类 号：R619[医药卫生—外科学]