Scalable fabrication of graphene-assembled multifunctional electrode with efficient electrochemical detection of dopamine and glucose  

作　　者：Xiaodong Ji Xin Zhao Zixin Zhang Yunfa Si Wei Qian Huaqiang Fu Zibo Chen Zhe Wang Huihui Jin Zhugen Yang Daping He 

机构地区：[1]State Key Laboratory of Silicate Materials for Architectures,Wuhan University of Technology,Wuhan 430070,China [2]Hubei Engineering Research Center of RF-Microwave Technology and Application,Wuhan University of Technology,Wuhan 430070,China [3]State Key Laboratory of Advanced Technology for Materials Synthesis and Processing,Wuhan University of Technology,Wuhan 430070,China [4]School of Information Engineering,Wuhan University of Technology,Wuhan 430070,China [5]School of Water,Energy and Environment,Cranfield University,Milton Keynes,MK430AL,UK

出　　处：《Nano Research》2023年第5期6361-6368,共8页纳米研究（英文版）

基　　金：the National Natural Science Foundation of China(Nos.51672204 and 22102128);the Fundamental Research Funds for the Central Universities(WUT:2021IVA66,WUT:2022IVA172,and WUT:2020IB005);the Hainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City(No.520LH054).

摘　　要：Conventional glassy carbon electrodes(GCE)cannot meet the requirements of future electrodes for wider use due to low conductivity,high cost,non-portability,lack of flexibility.Therefore,cost-effective and wearable electrode enabling rapid and versatile molecule detection is becoming important,especially with the ever-increasing demand for health monitoring and point-ofcare diagnosis.Graphene is considered as an ideal electrode due to its excellent physicochemical properties.Here,we prepare graphene film with ultra-high conductivity and customize the 3-electrode system via a facile and highly controllable laser engraving approach.Benefiting from the ultra-high conductivity(5.65×10^(5)S·m^(−1)),the 3-electrode system can be used as multifunctional electrode for direct detection of dopamine(DA)and enzyme-based detection of glucose without further metal deposition.The dynamic ranges from 1–200μM to 0.5–8.0 mM were observed for DA and glucose,respectively,with a limit of detection(LOD)of 0.6μM and 0.41 mM.Overall,the excellent target detection capability caused by the ultra-high conductivity and ease modification of graphene films,together with their superb mechanical properties and ease of mass-produced,provides clear potential not only for replacing GCE for various electrochemical studies but also for the development of portable and highperformance electrochemical wearable medical devices.

关 键 词：graphene film ultra-high conductivity multifunctional electrode point-of-care diagnosis wearable medical devices 

分 类 号：O64[理学—物理化学]