口服钙通道阻滞剂类药品临床综合评价专家共识(湖南)  

Expert consensus on clinical comprehensive evaluation of oral CCBs(Hunan)

作　　者：周凌云[1,2] 邓晟 徐萍[4] 李昕[5] 颜滢 欧阳林旗 刘湘[8] 何鸽飞 陈艳平 史志华[11] 王安发[12] 黄宇[13] 王立新[14] 何益锋 张继红[16] 郭艳 左笑丛[1,2] ZHOU Ling-yun;DENG Sheng;XU Ping;LI Xin;YAN Ying;OUYANG Lin-qi;LIU Xiang;HE Ge-fei;CHEN Yan-ping;SHI Zhi-hua;WANG An-fa;HUANG Yu;WANG Li-xin;HE Yi-feng;ZHANG Ji-hong;GUO Yan;ZUO Xiao-cong(Department of Pharmacy,The Third Xiangya Hospital,Central South University,Hunan Changsha 410013,China;Hunan Drug Clinical Comprehensive Evaluation Center,Hunan Changsha 410013,China;Department of Pharmacy,Xiangya Hospital,Central South University,Hunan Changsha 410008,China;Department of Pharmacy,The Second Xiangya Hospital,Central South University,Hunan Changsha 410012,China;Department of Pharmacy,Changsha Third Hospital,Hunan Changsha 410035,China;Department of Pharmacy,Hengyang Central Hospital,Hunan Hengyang 421001,China;Department of Pharmacy,The First Hospital Affiliated to Hunan University of Chinese Medicine,Hunan Changsha 410021,China;Department of Pharmacy,Xiangtan Central Hospital,Hunan Xiangtan 411199,China;Department of Pharmacy,The First Hospital of Changsha,Hunan Changsha 410005,China;Department of Pharmacy,Changsha Central Hospital,Hunan Changsha 410028,China;Department of Pharmacy,The First People's Hospital of Huaihua,Hunan Huaihua 418099,China;Department of Pharmacy,The First People's Hospital of Chenzhou,Hunan Chenzhou 423099,China;Department of Pharmacy,Hunan Brain Hospital,Hunan Changsha 410021,China;Department of Pharmacy,Yueyang Central Hospital,Hunan Yueyang 414020,China;Department of Pharmacy,The First People's Hospital of Changde City,Hunan Changde 415003,China;Department of Pharmacy,The Central Hospital of Shaoyang,Hunan Shaoyang 422099,China;Department of Pharmacy,Taoyuan People's Hospital,Hunan Changde 415799,China)

机构地区：[1]中南大学湘雅三医院药学部,湖南长沙410013 [2]湖南省药品临床综合评价中心,湖南长沙410013 [3]中南大学湘雅医院药学部,湖南长沙410008 [4]中南大学湘雅二医院药学部,湖南长沙410012 [5]长沙市第三医院药剂科,湖南长沙410035 [6]衡阳市中心医院药学部,湖南衡阳421001 [7]湖南中医药大学第一附属医院药剂科,湖南长沙410021 [8]湘潭市中心医院药剂科,湖南湘潭411199 [9]长沙市第一医院药剂科,湖南长沙410005 [10]长沙市中心医院药剂科,湖南长沙410028 [11]怀化市第一人民医院药剂科,湖南怀化418099 [12]郴州市第一人民医院药剂科,湖南郴州423099 [13]湖南省脑科医院药剂科,湖南长沙410021 [14]岳阳市中心医院药剂科,湖南岳阳414020 [15]常德市第一人民医院药剂科,湖南常德415003 [16]邵阳市中心医院药剂科,湖南邵阳422099 [17]桃源县人民医院药剂科,湖南常德415799

出　　处：《中国医院药学杂志》2023年第7期711-733,737,共24页Chinese Journal of Hospital Pharmacy

基　　金：药源性器官损伤智能防控湖南省工程研究中心(No.40)。

摘　　要：口服钙通道阻滞剂(calcium channel blocker,CCB)为最常见的心血管疾病长期用药。因此,有必要针对品种繁多的口服CCB类药品构建科学、规范的临床综合评价体系,并制定《口服CCB类药品临床综合评价专家共识》(下称“共识”),供决策部门及临床参考。中南大学湘雅三医院联合部、省级和各地、州、市、县共16家代表医疗机构成立了共识编写委员会,参考《药品临床综合评价管理指南》以及《心血管病药品临床综合评价技术指南》,基于最新的循证医学证据,主要针对高血压和冠心病适应证,从有效性、安全性、经济性、可及性、适宜性以及创新性6个维度开展了口服CCB类药品的综合评价,并广泛征求了药学和临床专家建议,最终制定本共识。本共识可为该类药品的临床合理用药以及医疗机构目录遴选提供指导建议和决策依据,为其他药品的综合评价体系的构建提供参考。Oral calcium channel blocker(CCB)is the most common long-term medication for cardiovascular diseases.Consequently,it is essential to construct a scientific and standardized clinical comprehensive evaluation system,and then formulate Expert Consensus on Clinical Comprehensive Evaluation of Oral CCBs to assist decision-making for the government and clinicians.The Third Xiangya Hospital of Central South University has organized the formulation of this expert consensus based on the Guideline for Clinical Comprehensive Evaluation of Medicine and Technical Guidelines for Clinical Comprehensive Evaluation of Medicine of Cardiovascular Diseases with the participation of 16 representative medical institutions in Hunan.The expert consensus systematically evaluated oral CCBs,especially in the therapy of hypertension and coronary artery diseases,from 6 dimensions,including safety,effectiveness,economy,accessibility,suitability and innovation.This expert consensus can provide a decision-making basis for the clinical rational drug use and selection of drugs for medical institutions,and provide reference for the construction of comprehensive evaluation system of other drugs.

关 键 词：钙通道阻滞剂 综合评价 共识 

分 类 号：R972[医药卫生—药品]