核素肾小球滤过率法在临床开展的现状与思考  

Current situation and reflection of nuclide labeled glomerular filtration rate method

作　　者：程旭[1] 俞悦 裴小华 Cheng Xu;Yu Yue;Pei Xiaohua(Department of Nuclear,the First Affiliated Hospital of Nanjing Medical University,Nangjing 210029,China;Department of Geriatric Nephrology,the First Affiliated Hospital of Nanjing Medical University,Nangjing 210029,China)

机构地区：[1]南京医科大学第一附属医院核医学科,210029 [2]南京医科大学第一附属医院老年肾科

出　　处：《中华诊断学电子杂志》2023年第2期73-76,共4页Chinese Journal of Diagnostics(Electronic Edition)

基　　金：中华医学会临床医学科研专项资金(15020020590);江苏省医学青年人才项目(QNRC2016592);江苏干部保健科研课题(BJ16016)。

摘　　要：通过血清肌酐和/或血清胱抑素C等参数估算肾小球滤过率(GFR)已在临床广泛应用,但在测算分肾功能、反映GFR真实水平方面仍无法替代基于核素的GFR测定方法。核素GFR测定方法分为核素肾动态显像法和核素血浆清除率法。这两种方法各有优缺点,本文将客观、全面地介绍其特点,以便临床医师合理使用。Although serum creatinine and/or serum cystatin C have been widely used in clinical practice to estimate glomerular filtration rate(GFR),they cannot replace nuclide labeled GFR measurement when measuring independent renal function and reflecting the true level of GFR.Nuclide labeled GFR methods include nuclide renal dynamic imaging method and nuclide plasma clearance method.These two methods have their own advantages and disadvantages,thus,we expect to objectively and comprehensively introduce their characteristics for rational use by clinicians.

关 键 词：肾小球滤过率 核素 肾功能 肌酐 胱抑素C 

分 类 号：R692[医药卫生—泌尿科学]