微针法表皮移植应用的新进展  

New progress in application of epidermal transplantation via microneedle techniques

作　　者：王雪 程微 苏建东[1] Wang Xue;Cheng Wei;Su Jiandong(Department of Burn and Plastic Surgery,Suzhou Hospital Affiliated to Nanjing Medical University,Suzhou 215000,China;School of Physical Science and Technology,Soochow University,and Jiangsu Key Laboratory of Thin Films,Suzhou 215006,China)

机构地区：[1]南京医科大学附属苏州医院烧伤整形科,苏州215000 [2]苏州大学物理科学与技术学院江苏省薄膜重点实验室,苏州215006

出　　处：《中华损伤与修复杂志（电子版）》2023年第3期270-273,共4页Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)

摘　　要：皮肤移植是烧创伤、慢性创面修复的主要方法,特别在大面积烧伤创面治疗中,植皮扩展比例、供区愈合时间、供受区瘢痕形成及手术疼痛等瓶颈问题亟待解决。本文综述微针技术的应用现状及皮肤移植技术的新进展,并介绍一种硅基微针负压提取法进行自体表皮移植的研究现状。Skin grafting is the main method of repairing burn wounds and chronic wounds,especially in the treatment of large-scale burns,the bottleneck problems such as skin graft expansion ratio,donor site healing time,scar formation in donar site and recipient area and surgical pain need to be solved urgently.This review summarizes the application status of microneedle technology and the new progress of skin transplantation,and focuses on the research progress of autologous epidermal transplantation by silicon-based microneedle negative pressure extraction.

关 键 词：微针 表皮移植 组织工程皮肤 创面修复 

分 类 号：R622[医药卫生—整形外科]