心脏MR T_(1) mapping技术在肥厚型心肌病与高血压性心脏病的诊断价值  

The diagnostic value of cardiac MR T_(1)mapping in hypertrophic cardiomyopathy and hypertensive heart disease

作　　者：梁学恒 高世平 石思玮 LIANG Xueheng;GAO Shiping;SHI Siwei(Department of Radiology,the People's Hospital of Chongqing Banan District,Chongqing 401320,China)

机构地区：[1]重庆市巴南区人民医院放射科,重庆401320

出　　处：《实用放射学杂志》2023年第4期566-570,共5页Journal of Practical Radiology

摘　　要：目的研究T_(1)mapping技术对肥厚型心肌病(HCM)与高血压心脏病(HHD)进行鉴别诊断并评估发现心肌纤维化的价值。方法回顾性收集24例HCM患者、24例HHD患者及正常对照25例的心脏磁共振(CMR)图像。测量受检者心肌的初始T1值,并分析各组间初始T_(1)值的差异。分析HCM与HHD心肌厚度与初始T_(1)值的相关性。采用受试者工作特征(ROC)曲线评估初始T_(1)值鉴别HCM、HDD的诊断效能。结果HCM肥厚组初始T1值高于HCM非肥厚组(P<0.001);HHD肥厚组初始T_(1)值高于HHD非肥厚组(P<0.001);HCM肥厚组初始T_(1)值高于HHD肥厚组(P<0.001)。HCM与HHD心肌厚度与初始T1值呈正相关(P<0.001)。心肌初始T_(1)值诊断HCM与HHD的曲线下面积(AUC)、敏感度、特异度分别为0.812、83.3%、75.0%。结论HCM与HHD随着心肌纤维化的进展,左心室肥厚(LVH)程度加重。T_(1)mapping的初始T1值可以定量鉴别诊断HCM与HHD。Objective To study the value of T_(1)mapping technology in the differential diagnosis of hypertrophic cardiomyopathy(HCM)and hypertensive heart disease(HHD),and to evaluate the value in detecting myocardial fibrosis.Methods The cardiac magnetic resonance(CMR)images of 24 HCM patients,24 HHD patients and 25 normal controls were retrospectively collected.The initial T_(1) value of the subject's myocardium was measured,and the difference in the initial T_(1) value between the groups was analyzed.The correlations between myocardial thickness and initial T_(1) values of HCM and HHD were analyzed.The receiver operating characteristic(ROC)curve was used to evaluate the diagnostic efficacy of the initial T_(1) value in distinguishing HCM and HDD.Results The initial T,value of the HCM hypertrophy group was higher than that of the control group(P<0.O01);the initial T_(1) value of the HHD hypertrophy group was higher than that of the control group(P<0.001);the initial T_(1) value of the HCM hypertrophy group was higher than that of the HHD hypertrophy group(P<0.001).HCM and HHD myocardial thickness were positively correlated with the initial T_(1) value(P<0.001).The area under the curve(AUC),sensitivity,and specificity of the initial T_(1) value of myocardium in the diagnosis of HCM and HHD were 0.812,83.3%,and 75.0%,respectively.Conclusion With the progress of myocardial fibrosis,the degree of left ventricular hypertrophy(LVH)of HCM and HHD patients becomes more severe.The initial T_(1) value of T_(1)mapping can quantitatively differentiate and diagnose HCM and HHD.

关 键 词：肥厚型心肌病 高血压性心脏病 心肌纤维化 心脏磁共振 T_(1)mapping 

分 类 号：R542.2[医药卫生—心血管疾病] R541.3[医药卫生—内科学] R445.2[医药卫生—临床医学]