脑血管病介入术后患者服用抗血小板药物的依从性及其影响因素分析  

Analysis of compliance of patients taking antiplatelet drugs after cerebrovascular disease interventional surgery and its risk factors

作　　者：何凤鸣 冯灵 汪锐 胡发云[2] 吴娟 刘勤 周乾晓 卫丹 曹乐 He Fengming;Feng Ling;Wang Rui;Hu Fayun;Wu Juan;Liu Qin;Zhou Qianxiao;Wei Dan;Cao Le(West China School of Nursing,Sichuan University/Department of Neurology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China;Department of Neurology Intervention Center,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)

机构地区：[1]四川大学华西护理学院/四川大学华西医院神经内科,四川成都610041 [2]四川大学华西医院神经内科介入中心,四川成都610041

出　　处：《血管与腔内血管外科杂志》2023年第4期441-444,459,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的 探讨脑血管病介入术后患者服用抗血小板药物的依从性及其影响因素。方法 收集2021年9月至2022年5月于四川大学华西医院进行介入治疗的180例脑血管病患者的临床资料,按照依从性的不同将患者分为良好组(n=131)和不佳组(n=49)。比较两组患者入院时的基本临床特征和随访结局,分析脑血管病介入术后患者服用抗血小板药物依从性不佳的影响因素。结果 良好组患者的年龄、初中及以下文化程度的比例及出院时认知功能下降的比例均低于不佳组患者,差异均有统计学意义(P﹤0.05)。不佳组患者脑卒中的发生率高于良好组患者,差异有统计学意义(P﹤0.05)。多因素分析结果显示,年龄≥65岁、初中及以下文化程度、出院时认知功能下降均是脑血管病介入术后患者服用抗血小板药物依从性不佳的独立危险因素(P﹤0.05)。结论 年龄≥65岁、初中及以下文化程度及出院时认知功能下降的患者脑血管病介入术后服用抗血小板药物的依从性差,应密切关注,督促服药。Objective To investigate the compliance of patients taking antiplatelet drugs after cerebrovascular disease interventional surgery and its risk factors.Method The clinical data of 180 patients with cerebrovascular disease who underwent interventional therapy at West China Hospital,Sichuan University from September 2021 to May 2022 were collected,patients were divided into good group(n=131)and poor group(n=49)according to their compliance.The baseline data of the two groups of patients on admission and follow-up outcomes were compared.Analyze the risk factors of poor compliance to antiplatelet drugs in patients with cerebrovascular disease after intervention surgery.Result The age,the proportion of junior high school and below education,and the proportion of cognitive decline at discharge in the good group were significantly lower than those in the poor group,and the difference was statistically significant(P<0.05).Multivariate analysis showed that age≥65 years,junior high school and below education and cognitive decline at discharge were risk factors for poor compliance with antiplatelet drugs during the six-month follow-up period after cerebrovascular disease interventional surgery.Conclusion The patients of age≥65 years,junior high school and below education,and cognitive decline at discharge have poor compliance with antiplatelet drugs after cerebrovascular interventional surgery,and thus they should be closely monitored and supervised.

关 键 词：脑血管 介入术 急性缺血脑卒中 抗血小板药物 依从性 

分 类 号：R543[医药卫生—心血管疾病]