血管腔内介入治疗联合负压闭式引流对糖尿病足创面的临床效果观察  

Observation of the clinical efficacy of endovascular intervention combined with negative pressure closed drainage in the treatment of diabetes foot wounds

作　　者：李涛 林海阳 赵景峰 Li Tao;Lin Haiyang;Zhao Jingfeng(Department of Repair and Reconstruction Surgery,Peking University Shougang Hospital,Beijing 100166,China)

机构地区：[1]北京大学首钢医院修复重建外科,北京100166

出　　处：《血管与腔内血管外科杂志》2023年第4期484-487,共4页Journal of Vascular and Endovascular Surgery

摘　　要：目的 观察血管腔内介入治疗联合负压闭式引流对糖尿病足创面的疗效与安全性。方法 收集2022年5月2022年11月于北京大学首钢医院住院治疗的35例糖尿病足患者的临床资料,根据住院期间治疗方案的不同将患者分为联合组(n=16,在保守治疗的基础上给予血管腔内介入联合负压闭式引流治疗)和对照组(n=19,给予保守治疗)。观察并比较两组患者治疗后1、3个月的创面愈合率、踝肱指数,治疗后3个月的截肢率、6分钟步行距离及血管腔内介入治疗后并发症发生情况。结果 两组患者的各种药物使用情况比较,差异均无统计学意义(P﹥0.05)。联合组患者治疗后1、3个月的创面愈合率、踝肱指数均高于对照组患者,差异均有统计学意义(P﹤0.05)。联合组患者治疗后3个月的截肢率低于对照组患者,6分钟步行距离长于对照组患者,差异均有统计学意义(P﹤0.05)。联合组患者血管腔内介入治疗后发生了并发症,包括穿刺点血肿2例,患肢肿胀疼痛2例,经对症治疗后均有所好转。结论 血管腔内介入治疗联合负压闭式引流对糖尿病足创面具有较好的疗效与安全性,值得临床推广。Objective To observe the efficacy and safety of endovascular intervention combined with negative pressure closed drainage in the treatment of diabetic foot wounds.Method The clinical data of 35 patients with diabetic foot who were hospitalized in Peking University Shougang Hospital from May 2022 to November 2022 were collected,the patients were divided into the combination group(n=16,given endovascular intervention combined with negative pressure closed drainage therapy on the basis of conservative treatment)and the control group(n=19,given conservative treatment)according to different treatment regimens during hospitalization.The wound healing rate,ankle-brachial index at one and three months after the treatment,amputation rate and 6-minute walking distance at three months after the treatment,complications after endovascular intervention therapy were observed and compared between the two groups.Result There was no statistically significant difference in drug use between two groups(P>0.05).The wound healing rate and anklebrachial index of combination group were higher than those of control group one month and three months after treatment,the differences were statistically significant(P<0.05).The amputation rate of patients in combination group was lower than that in control group three months after treatment,and the 6-minute walking distance was longer than that in control group,with statistical significance(P<0.05).Complications occurred in the combination group after endovascular intervention,including 2 cases of puncture point hematoma and 2 cases of affected limb swelling and pain,after symptomatic treatment,all of which were improved.Conclusion Endovascular intervention combined with negative pressure closed drainage in the treatment of diabetic foot wounds has a good curative effect and safety,and is worthy of clinical promotion.

关 键 词：血管腔内介入治疗 负压闭式引流 糖尿病足 创面 临床疗效 安全性 

分 类 号：R543[医药卫生—心血管疾病]