江苏省老年2型糖尿病患者血压分布及关联因素分析  

The distribution of blood pressure and associated factors of the elderly with type 2 diabetes in Jiangsu Province

作　　者：刘佳慧 谢涵坤 苏健[2] 朱政[2] 潘恩春[3] 陆艳[4] 万福萍 颜庆洋 张宁[7] 顾淑君[7] 武鸣[2] 周金意[2] 沈冲 Liu Jiahui;Xie Hankun;Su Jian;Zhu Zheng;Pan Enchun;Lu Yan;Wan Fuping;Yan Qingyang;Zhang Ning;Gu Shujun;Wu Ming;Zhou Jinyi;Shen Chong(Department of Epidemiology,School of Public Health,Nanjing Medical University,Nanjing 211166,China;Department of Non-communicable Chronic Disease Control,Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210009,China;Center for Disease Control and Prevention of Huai′an City,Huai′an 223002,China;Department of Non-communicable Chronic Disease Control,Center for Disease Control and Prevention of Suzhou City,Suzhou 215004,China;Department of Non-communicable Chronic Disease Control,Center for Disease Control and Prevention of Qingjiangpu District in Huai′an City,Huai′an 223021,China;Department of Non-communicable Chronic Disease Control,Center for Disease Control and Prevention of Huai′an District in Huai′an City,Huai′an 223229,China;Center for Disease Control and Prevention of Changshu and Suzhou City,Suzhou 215500,China)

机构地区：[1]南京医科大学公共卫生学院流行病学系,南京211166 [2]江苏省疾病预防控制中心慢性非传染病防制所,南京210009 [3]江苏省淮安市疾病预防控制中心,淮安223002 [4]江苏省苏州市疾病预防控制中心慢性非传染病防治科,苏州215004 [5]江苏省淮安市清江浦区疾病预防控制中心慢性非传染病防治科,淮安223021 [6]江苏省淮安市淮安区疾病预防控制中心慢性非传染病防治科,淮安223299 [7]江苏省苏州市常熟市疾病预防控制中心,苏州215500

出　　处：《中华预防医学杂志》2023年第5期614-625,共12页Chinese Journal of Preventive Medicine

基　　金：江苏省卫生厅医学创新团队科技项目(K201105);中国中部地区主动健康云平台示范应用与评价(2018YFC2000703)。

摘　　要：目的探讨江苏省老年2型糖尿病(T2DM)患者的血压分布情况及影响血压的关联因素。方法选取江苏省淮安市和苏州常熟市社区≥60岁T2DM患者为研究对象进行横断面调查,将研究对象分为服用降压药和未服用降压药2组。采用调查问卷的方法收集研究对象的年龄、性别等人口学特征和关联因素,并通过体格检查测量收缩压和舒张压。分别描述男女各年龄组收缩压和舒张压的百分位数;绘制核密度估计图呈现血压分布情况;采用局部加权回归拟合血压随年龄的变化趋势;采用logistic回归模型分析血压的关联因素。结果共纳入研究对象12949例,服用降压药7775例,未服用降压药5174例。研究对象收缩压集中分布于140~160 mmHg,舒张压集中分布于75~85 mmHg。在服用降压药和未服用降压药两组中,老年T2DM患者血压分布在BMI和城乡亚组间差异均有统计学意义。<80岁老年T2DM患者,收缩压呈现出随年龄增长而上升的趋势,舒张压呈现出随年龄增长而下降的趋势。年龄升高、BMI≥24 kg/m^(2)、空腹血糖≥7.0 mmol/L、居住农村及不吸烟是收缩压升高的关联因素;BMI≥24 kg/m^(2)、男性、居住农村、不吸烟、饮酒及未接受药物降糖治疗是舒张压升高的关联因素。结论江苏省老年T2DM患者的收缩压处于较高水平,在服用降压药组中,其血压的分布有明显的男女性别差异,且在60~80岁年龄段收缩压呈上升趋势,舒张压呈下降趋势。该人群的血压水平受年龄、BMI、城乡、吸烟状态等关联因素的影响。Objective To investigate the distribution of blood pressure and analyze the associated factors of blood pressure of the elderly with type 2 diabetes in Jiangsu Province.Methods The elderly over 60 years old participants with type 2 diabetes in the communities of Huai′an City and Changshu City,Jiangsu Province were selected in this study.They were divided into two groups:taking antihypertensive drugs and not taking antihypertensive drugs.The demographic characteristics,such as age and sex,and relevant factors were collected by questionnaire.The systolic blood pressure(SBP)and diastolic blood pressure(DBP)were measured by physical examination.The percentile of SBP and DBP in each age group of men and women were described.The kernel density estimation curve was used to show the blood pressure distribution.The trend of blood pressure with age was fitted by locally weighted regression.The logistic regression model was used to analyze relevant factors of blood pressure.Results A total of 12949 participants were included in this study,including 7775 patients in the antihypertensive drug group and 5174 patients in the group without antihypertensive drugs.The SBP of participants was concentrated at 140-160 mmHg,and their DBP was concentrated at 75-85 mmHg.There were significant differences in the distribution of blood pressure among the subgroups of body mass index(BMI)and rural areas whether taking antihypertensive drugs and not.For participants aged under 80 years old,the SBP showed an increasing trend with age and the DBP showed a decreasing trend with age.Age,BMI≥24 kg/m^(2),fasting blood glucose≥7.0 mmol/L,living in rural areas and no smoking were influencing factors of the elevated SBP;BMI≥24 kg/m^(2),male,living in rural areas,no smoking,drinking alcohol and not receiving drug hypoglycemic treatment were influencing factors of the elevated DBP.Conclusion The SBP of older diabetic adults in Jiangsu Province is at a high level,and the distribution of blood pressure is significantly different between men and w

关 键 词：2型糖尿病 老年人 血压 关联因素 横断面研究 

分 类 号：R587.1[医药卫生—内分泌]