儿童青少年肥胖干预措施的研究进展  

Research progresses on interventions of obesity in children and adolescents

作　　者：万乃君[1] 张田[1] Wan Naijun;Zhang Tian(Department of Pediatrics,Beijing Jishuitan Hospital,Beijing 100035,China)

机构地区：[1]北京积水潭医院儿科,北京100035

出　　处：《中华预防医学杂志》2023年第5期760-765,共6页Chinese Journal of Preventive Medicine

基　　金：北京市医院管理中心儿科学科协同发展中心专项经费资助(XTZD20180401)。

摘　　要：儿童青少年肥胖已经成为一种全球流行病,干预手段主要包括生活方式干预、药物治疗和手术治疗三个方面。其中生活方式干预,尤其是家庭参与的强化生活方式干预是儿童青少年肥胖的一线治疗方法。药物治疗和外科手术是严重肥胖儿童青少年的辅助治疗手段。目前治疗儿童青少年肥胖国内外临床应用最多的药物为二甲双胍,国外应用较多且安全性较高的药物还有奥利司他、利拉鲁肽,其他药物均不推荐。手术治疗作为肥胖的三级预防治疗措施,应在患儿及其家属具有良好的依从性,多学科合作共同配合下进行,常用的术式为袖状胃切除术(SG),Roux-en-Y胃旁路术(RYGB);球囊内镜作为新兴的治疗方式有待进一步关注其疗效及安全性。Childhood and adolescent obesity has become a global epidemic.The interventions mainly include lifestyle intervention,medication treatment and bariatric surgery.Among them,lifestyle intervention,especially intensive lifestyle intervention with participation of family members,is the first-line treatment for obesity in children and adolescents.Both medication and bariatric surgery are adjuvant treatments for severely obese children and adolescents.Currently,metformin is the most widely used drug for the treatment of obesity in children and adolescents in both China and other countries;orlistat and liraglutide are also the drugs that are safe and often used in other countries;other drugs are not recommended.As a tertiary prevention and treatment strategy for obesity,bariatric surgery should be carried out on the basis of good compliance from both the children and their family members,with the cooperation of multiple disciplines.Sleeve gastrectomy(SG)and Roux-en-Y gastric bypass(RYGB)are the most common types of procedure performed.Meanwhile,as a new treatment method,intra-gastric balloon procedure needs to be paid more attention to its efficacy and safety.

关 键 词：肥胖 儿童青少年 生活方式干预 药物治疗 手术治疗 

分 类 号：R723.14[医药卫生—儿科]